MIR338, microRNA 338, 442906

N. diseases: 128; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C0023891
Disease: Liver Cirrhosis, Alcoholic
Liver Cirrhosis, Alcoholic
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
0.300 Biomarker phenotype CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
Chemical and Drug Induced Liver Injury
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker disease CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106 2017
CUI: C0019207
Disease: Hepatoma, Morris
Hepatoma, Morris
0.300 Biomarker disease CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0019208
Disease: Hepatoma, Novikoff
Hepatoma, Novikoff
0.300 Biomarker disease CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental
0.300 Biomarker phenotype CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions
0.300 Biomarker group CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0086404
Disease: Experimental Hepatoma
Experimental Hepatoma
0.300 Biomarker disease CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0282313
Disease: Condition, Preneoplastic
Condition, Preneoplastic
0.300 Biomarker disease CTD_human Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. 21035526 2011
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression disease BEFREE Over-expression of miR-338-5p promotes CRC metastasis to the liver and lung in vivo, in which PIK3C3 was down-regulated in the metastatic tumours. 30982765 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression disease BEFREE In conclusion, miR-338-3p expression was decreased in CRC. miR-338-3p regulated the proliferation, apoptosis and migration of CRC cells by targeting MACC1. 30906469 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression disease BEFREE In this study, the unbiased miRNA array screening revealed that miR-338-5p is downregulated in both hypoxic CRC cell lines tested. 31208913 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker phenotype BEFREE Mir-371, mir-150, mir-21 and mir-7d were found to be potential prognostic markers, while mir-134, mir-146a, mir-338 and mir-371 were associated with metastases. 30579238 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression phenotype BEFREE Over-expression of miR-338-5p promotes CRC metastasis to the liver and lung in vivo, in which PIK3C3 was down-regulated in the metastatic tumours. 30982765 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 AlteredExpression phenotype BEFREE Further, the underlying mechanism showed that circ_0000003 functioned as endogenous competitive RNA and directly targeted miR-338-3p to positively regulated IRS2 expression.<b>Conclusion</b>: Circ_0000003 promotes the proliferation and metastasis of NSCLC cells via modulating miR-338-3p/IRS2 axis. 31736412 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker phenotype BEFREE MicroRNA-338-3p inhibits tumor growth and metastasis in osteosarcoma cells by targeting RUNX2/CDK4 and inhibition of MAPK pathway. 30484892 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker phenotype BEFREE The present data indicated that restoration of miR-338-3p could suppress the growth and metastasis of ovarian cancer cells, which might due to the inhibition of proliferation and EMT induced by MACC1, Met and its downstream Wnt/Catenin beta and MEK/ERK signaling pathways. 31842953 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker phenotype BEFREE And upregulation of ETS1 partially rescued the suppression of miR-338-3p for cell proliferation and metastasis in BC. 30915741 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.100 Biomarker phenotype BEFREE The purpose of this study was to evaluate the potential value of a panel of HCC-related circulating miRNAs (miR-142, miR-182, miR-200a, mir-210, miR-211, miR-302b, miR-324, miR-338, miR-340 and miR-1246) as noninvasive biomarkers for discriminating primary HCC from metastatic tumors in the liver. 30867638 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 Biomarker group BEFREE Serum miR-338-5p has the potential to be a tumor marker of RB, and, in combination with NSE, miR-338-5p may improve the early diagnosis rate of RB. 31289501 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.100 AlteredExpression group BEFREE Finally, a xenograft tumor model was developed to explore the effects of overexpression of miR-338-3p on tumor growth in ovarian cancer in vivo. 31769245 2019