|
Asthma
|
0.430 |
Biomarker
|
disease |
HPO |
|
|
|
|
Asthma
|
0.430 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Caries (morphologic abnormality)
|
0.020 |
Biomarker
|
disease |
BEFREE |
<b>Purpose</b>: Data currently available indicate the significance of salivary mucins MUC5B and MUC7 in the protection of teeth against caries.
|
30745804 |
2019 |
|
Craniosynostosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
(4) Mucin glycoprotein MUC7 that has known bactericidal activity displays an overall reduced terminal sugar profile in biofilm positive CRS patients.
|
21244730 |
2011 |
|
Adenocarcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
MUC7 expression was highly significant for adenocarcinoma (P=0.007) and borderline for IPMN (P=0.05).
|
21647207 |
2011 |
|
Pancreatitis, Chronic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MUC7 was expressed in 37.5% of chronic pancreatitis cases.
|
21647207 |
2011 |
|
Adenocarcinoma of pancreas
|
0.010 |
Biomarker
|
disease |
BEFREE |
MUC7 could serve as a potential biological marker to identify malignant lesions, especially pancreatic adenocarcinoma.
|
21647207 |
2011 |
|
Burning Mouth Syndrome
|
0.020 |
Biomarker
|
disease |
BEFREE |
MUC7 O-glycans and measured inflammatory biomarkers were found to be similar between BMS and controls.
|
31414088 |
2019 |
|
Asthma
|
0.430 |
GeneticVariation
|
disease |
BEFREE |
A logistic regression analysis showed that the MUC7*5-VNTR allele decreased the likelihood of a diagnosis of asthma (odds ratio, 0.173 [95% confidence interval, 0.041-0.737]; P < 0.018) and is not in a strong linkage disequilibrium with the rs9982010 (r = 0.03; odds ratio, 66; confidence interval, 5.913-736.72).
|
19820409 |
2009 |
|
Carcinogenesis
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
A membrane-bound mucin MUC15 and secreted mucins MUC4 and MUC7 are known to involve in tumorigenesis, but their mutation status in cancers remains unknown.
|
25573589 |
2015 |
|
Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Cells from the urine of 65 patients with bladder cancer, 15 patients with a negative bladder biopsy for bladder cancer, and 30 healthy volunteers were compared for the following parameters: tumor stage, grade, size, and number, urinary cytology, and expression of MUC7.
|
12837463 |
2003 |
|
Human immunodeficiency virus (HIV) II infection category B1
|
0.010 |
Biomarker
|
disease |
BEFREE |
Crude saliva and its purified mucins, MUC5B and MUC7, and the purified mucins from breast milk, MUC1 and MUC4 and pregnancy plug cervical mucus (MUC2, MUC5AC, MUC5B and MUC6), inhibit HIV-1 in an in vitro assay.
|
28985745 |
2017 |
|
Carcinoma of bladder
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma.
|
9865718 |
1998 |
|
Chronic Periodontitis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Genetic polymorphism of MUC7 in individuals with aggressive or chronic periodontitis.
|
22167029 |
2011 |
|
Iron Overload
|
0.010 |
Biomarker
|
disease |
BEFREE |
Hence, the chelator could be used as chelating agent for iron overload situations without depleting essential metal ions, such as Mg(II) and Zn(II) ions.
|
28364616 |
2017 |
|
Chronic Kidney Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Histatin-1, Mucin-7 and aPRP 1/2 are expected to be candidate salivary biomarkers of CKD HD patients.
|
30529606 |
2019 |
|
Malignant Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
In a public database, we found that MUC15 and MUC7 genes had mononucleotide repeats in the coding sequences that might be mutation targets in the cancers with microsatellite instability (MSI).
|
25573589 |
2015 |
|
Carcinoma of urinary bladder, invasive
|
0.010 |
Biomarker
|
disease |
BEFREE |
In contrast to CK-20, analysis of MUC7 demonstrated a high sensitivity and high specificity for carcinoma in situ and invasive bladder cancer, thus fulfilling the criteria of a urinary tumor marker.
|
12478110 |
2003 |
|
Colorectal Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In the present study, we found MUC15 frameshift mutations (14.7% of GC and 15.2% of CRC with MSI-H), MUC 7 frameshift mutations (2.9% of GC with MSI-H) and MUC4 frameshift mutations (8.8% of GC and 3.8% of CRC with MSI-H).
|
25573589 |
2015 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Information is available on changes in the expression levels and distribution profiles of MUC1, MUC2, MUC3, MUC4, MUC5AC, MUC5B, MUC6 and MUC7 in tumors of the salivary glands; and of MUC1, MUC2 and MUC4 in HNSCC.
|
21723776 |
2011 |
|
Rhinitis, Vasomotor
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MUC1, MUC2, MUC4, MUC5AC, MUC5B, and MUC7 were expressed in both the normal and VMR turbinates.
|
9292181 |
1997 |
|
Laryngitis
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.
|
18834073 |
2008 |
|
Urinary tract infection
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Nested reverse transcription-polymerase chain reaction (RT-PCR) was performed on four types of bladder cancer cell lines (RT4, T24, EJ-1 and TCC) and the peripheral blood of 38 (31 superficial disease and seven invasive disease) bladder cancer patients and 18 subjects with urinary tract infections or other non-malignant conditions to determine the expression of MUC7.
|
14678183 |
2004 |
|
Recurrent urinary tract infection
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Nested reverse transcription-polymerase chain reaction (RT-PCR) was performed on four types of bladder cancer cell lines (RT4, T24, EJ-1 and TCC) and the peripheral blood of 38 (31 superficial disease and seven invasive disease) bladder cancer patients and 18 subjects with urinary tract infections or other non-malignant conditions to determine the expression of MUC7.
|
14678183 |
2004 |
|
Cystic Fibrosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
No remarkable differences were observed in the expression patterns of MUC5B or MUC7 between CF (n = 7) and non-CF (n = 10) bronchial samples.
|
9651178 |
1998 |