|
Age related macular degeneration
|
0.040 |
Biomarker
|
disease |
BEFREE |
Choroidal neovascularization (CNV) in adults is most commonly associated with neovascular age-related macular degeneration (AMD) and pathologic myopia.
|
30727875 |
2018 |
|
Age related macular degeneration
|
0.040 |
Biomarker
|
disease |
BEFREE |
The aim of this systematic literature review was to evaluate the efficacy and safety of interventions for the treatment of choroidal neovascularization (CNV) secondary to etiologies other than age-related macular degeneration and pathologic myopia.
|
29687336 |
2018 |
|
Age related macular degeneration
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Particularly, age-related macular degeneration (AMD) and pathologic myopia (PM) are the most frequent diseases related to CNV development.
|
20887247 |
2011 |
|
Age related macular degeneration
|
0.040 |
Biomarker
|
disease |
BEFREE |
The study population included patients affected by subfoveal CNV secondary to AMD or PM.
|
26307969 |
2015 |
|
Atrophoderma maculatum
|
0.010 |
Biomarker
|
disease |
BEFREE |
This postoperative MA might be a new complication of pathologic myopia.
|
31834131 |
2019 |
|
Blindness
|
0.040 |
GeneticVariation
|
phenotype |
BEFREE |
Myopic submacular hemorrhage (SMH) usually arises from either a break in Bruch's membrane (lacquer cracks) that damages the underlying choriocapillaris or the development of a choroidal neovascular membrane (CNVM) at the sites of prior lacquer cracks.1,2 In pathologic myopia (PM), axial elongation leads to thinning of the choroid and retinal pigment epithelium, predisposing to rupture of Bruch's membrane.3 If large hemorrhages involving the fovea are left untreated, subretinal hemorrhage and CNVM can cause devastating long-term vision loss due to irreversible retinal atrophy.4 In this video, the authors describe their technique of using a subretinal injection of recombinant tissue plasminogen activator with a concurrent gas tamponade to displace SMH.
|
30998250 |
2019 |
|
Blindness
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
Ocular alterations associated with pathologic myopia, especially those involving the macular area-defined as myopic maculopathy-are the leading causes of vision loss in patients with pathologic myopia.
|
30391362 |
2019 |
|
Blindness
|
0.040 |
Biomarker
|
phenotype |
BEFREE |
Development of myopic choroidal neovascularization (CNV) is one of the most common complications that leads to central vision loss in patients with pathologic myopia.
|
29111299 |
2018 |
|
Blindness
|
0.040 |
GeneticVariation
|
phenotype |
BEFREE |
The burden of myopia is tremendous, as adults with HM are more likely to develop pathologic myopia (PM) changes that can lead to blindness.
|
30707221 |
2019 |
|
Central retinal vein occlusion
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Aqueous humour from eyes with central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), diabetic macular oedema (DME), neovascular age-related macular degeneration (nAMD) or pathologic myopia associated choroidal neovascularization (pmCNV) was sampled prior to 1st (n = 144) and 2nd (n = 48) intravitreal anti-VEGF therapy.
|
31531945 |
2019 |
|
Chorioretinal atrophy
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Lacquer cracks detected in rge chicks subsequently progressed to patchy chorioretinal atrophy, which is also commonly seen in patients with pathologic myopia.
|
30586351 |
2019 |
|
Chorioretinal atrophy
|
0.030 |
Biomarker
|
disease |
BEFREE |
CLINICAL FEATURES OF PATCHY CHORIORETINAL ATROPHY IN PATHOLOGIC MYOPIA.
|
31166247 |
2019 |
|
Chorioretinal atrophy
|
0.030 |
Biomarker
|
disease |
BEFREE |
Amniotic membrane for retinal detachment due to paravascular retinal breaks over patchy chorioretinal atrophy in pathologic myopia.
|
31766876 |
2020 |
|
Choroidal neovascular membrane (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Myopic submacular hemorrhage (SMH) usually arises from either a break in Bruch's membrane (lacquer cracks) that damages the underlying choriocapillaris or the development of a choroidal neovascular membrane (CNVM) at the sites of prior lacquer cracks.1,2 In pathologic myopia (PM), axial elongation leads to thinning of the choroid and retinal pigment epithelium, predisposing to rupture of Bruch's membrane.3 If large hemorrhages involving the fovea are left untreated, subretinal hemorrhage and CNVM can cause devastating long-term vision loss due to irreversible retinal atrophy.4 In this video, the authors describe their technique of using a subretinal injection of recombinant tissue plasminogen activator with a concurrent gas tamponade to displace SMH.
|
30998250 |
2019 |
|
Choroidal retinal neovascularization
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Myopic submacular hemorrhage (SMH) usually arises from either a break in Bruch's membrane (lacquer cracks) that damages the underlying choriocapillaris or the development of a choroidal neovascular membrane (CNVM) at the sites of prior lacquer cracks.1,2 In pathologic myopia (PM), axial elongation leads to thinning of the choroid and retinal pigment epithelium, predisposing to rupture of Bruch's membrane.3 If large hemorrhages involving the fovea are left untreated, subretinal hemorrhage and CNVM can cause devastating long-term vision loss due to irreversible retinal atrophy.4 In this video, the authors describe their technique of using a subretinal injection of recombinant tissue plasminogen activator with a concurrent gas tamponade to displace SMH.
|
30998250 |
2019 |
|
Diabetic macular edema
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Aqueous humour from eyes with central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), diabetic macular oedema (DME), neovascular age-related macular degeneration (nAMD) or pathologic myopia associated choroidal neovascularization (pmCNV) was sampled prior to 1st (n = 144) and 2nd (n = 48) intravitreal anti-VEGF therapy.
|
31531945 |
2019 |
|
Disorder of eye
|
0.020 |
Biomarker
|
group |
BEFREE |
Although the terms high myopia and pathologic myopia are often used interchangeably, they do not refer to the same eye disease.
|
30391362 |
2019 |
|
Disorder of eye
|
0.020 |
Biomarker
|
group |
BEFREE |
Higher levels of myopia, usually defined as an axial eye length of >26 mm or a refractive error of < -5.00 diopters are often designated as 'pathologic' myopia, because of the predisposition to develop further eye disorders such as retinal detachment, macular degeneration, cataract, or glaucoma.
|
18360688 |
2008 |
|
Disorder of macula of retina
|
0.040 |
Biomarker
|
group |
BEFREE |
Within the pathologic myopia (PM) group (n = 521 eyes), progression of myopic maculopathy was associated with female gender (odds ratio [OR], 2.21; P = 0.001), older age (OR, 1.03; P = 0.002), longer axial length (OR, 1.20; P = 0.007), greater axial elongation (OR, 1.45; P = 0.005), and development of parapapillary atrophy (PPA; OR, 3.14; P < 0.001).
|
29371011 |
2018 |
|
Disorder of macula of retina
|
0.040 |
Biomarker
|
group |
BEFREE |
Myopic maculopathy was defined according to the criteria of the Meta-analysis of Pathologic Myopia Study Group classification system.
|
31260519 |
2019 |
|
Disorder of macula of retina
|
0.040 |
Biomarker
|
group |
BEFREE |
So, what is pathologic myopia?This review covers the various proposed definitions for pathologic myopia, and describes its major features such as posterior staphyloma, variation in axial length, and the presence of myopic maculopathy.
|
27755375 |
2017 |
|
Disorder of macula of retina
|
0.040 |
Biomarker
|
group |
BEFREE |
Myopic maculopathy was graded from fundus photographs according to the Meta-Analysis for Pathologic Myopia classification.
|
29952919 |
2019 |
|
Epiretinal Membrane
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The most common macular disorders were an epiretinal membrane (n = 130), myopia atrophy (n = 61) and a dome-shaped macular with pathologic myopia (n = 32).
|
29572456 |
2018 |
|
Exudative age-related macular degeneration
|
0.030 |
Biomarker
|
disease |
BEFREE |
Intravitreal ranibizumab is a highly cost-effective intervention for the treatment of CNV due to causes other than nAMD and PM as it delivers substantial QALY gains to patients while making cost savings vs. BSC.
|
30726549 |
2019 |
|
Exudative age-related macular degeneration
|
0.030 |
Biomarker
|
disease |
BEFREE |
Aqueous humour from eyes with central retinal vein occlusion (CRVO), branch retinal vein occlusion (BRVO), diabetic macular oedema (DME), neovascular age-related macular degeneration (nAMD) or pathologic myopia associated choroidal neovascularization (pmCNV) was sampled prior to 1st (n = 144) and 2nd (n = 48) intravitreal anti-VEGF therapy.
|
31531945 |
2019 |