NCAM1, neural cell adhesion molecule 1, 4684

N. diseases: 445; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE In this study we analysed the cytogenetic findings of seven patients with CD56-positive putative NK cell lymphoma/leukaemia. 9326190 1997
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE CD5-CD56+ T-cell receptor silent peripheral T-cell lymphomas are natural killer cell lymphomas. 8608237 1996
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE To describe the clinical, pathological and molecular features in six cases of CD56+ lymphoma with cutaneous presentation. 12653743 2003
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE CD16/CD56 expression without CD38<sup>higher</sup> and the lack of CD16/CD56 with CD38<sup>higher</sup> expression proves to be a reliable, fast, and cost-effective method for diagnosing 11q aberration and MYC rearrangements in CD10(+) aggressive lymphomas, respectively. 29327714 2018
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The diagnosis of NK cell lymphoma was made on the basis of morphological and immunological characteristics (CD3-CD56+) found on skin biopsy of one of multiple skin nodules which subsequently developed in association with splenomegaly, thrombocytopenia and continuing neutropenia. 9869207 1998
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Coexistence of two distinct cell populations (CD56(+)TcRgammadelta(+) and CD56(+)TcRgammadelta(-)) in a case of aggressive CD56(+) lymphoma/leukemia. 10800166 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE In type II EATL, lymphoma cells of the 16 (80%) and 11 (55%) cases were positive for CD56 and CD8, respectively. 21323966 2011
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Four patients with cutaneous CD4+ and CD56+ lymphoma were studied. 10828627 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Five CD3- CD56+ lymphoma patients presenting with nodular lesions were identified among 180 immunophenotyped cutaneous lymphomas. 9470917 1997
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE We report 4 cases of lymphomas/leukemias with the unusual CD56/CD4 phenotype. 11488062 2001
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE CD4+/CD56+ hematodermic neoplasm (HN), formerly known as a blastic natural killer (NK) cell lymphoma, is a rare subtype of a cutaneous dendritic cell neoplasm notable for highly aggressive behavior. 18005171 2008
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Thus, there seems to be a useful distinction between the classical NK/T type of nasal lymphoma (CD56+/n-cdk6+/CD44-/TcR-GR-) and PTL (CD56-/n-cdk6-/CD44+/TcR-GR+) involving the nasal region. 10879740 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE CD2+, CD3-, CD56/NCAM+ malignant lymphoma with TCR beta gene rearrangement: a case report. 7485082 1995
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE We consider that blastoid NK cell lymphoma is an extremely aggressive subtype of CD56-positive lymphomas, and high-dose chemotherapy with peripheral blood stem cell rescue should be included for the choice of the treatment. 10048432 1999
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Among these six cases, four female CD56(-)/CD44(-)/CD8(-)/CD45RO(+)/CD45RA(-) cases constituted a distinct group with a better prognosis than the rest of the male cases of sinonasal lymphomas. 12533686 2003
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE We report the clinical and laboratory findings of a patient with an aggressive Epstein-Barr virus positive CD2+/CD56+ natural killer-cell lymphoma with a high mitotic activity and complex chromosomal abnormalities presenting with life-threatening pericardial and pleural effusions, disseminated skin lesions, breast nodule and large suprarenal masses. 11911423 2002
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The aim of this work was to study the expression of human leukocyte antigen G (HLA-G) and interleukin 10 (IL-10) in conjunction with expression of HLA-G killer-cell inhibitory receptor ligand immunoglobulin-like transcript 2 (ILT2) in CD3+, CD19+, CD56+ lymphomas, and ILT4 in CD14+ cells from patients with systemic lupus erythematosus (SLE). 22562117 2013
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Expression of CD56 is associated with a poor prognosis in subcutaneous panniculitis-like T-cell lymphoma and blastic natural killer cell lymphoma. 17052504 2006
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Thus, EBV may play an etiologic role in these CD56-positive lymphomas. 7520016 1994
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE NCAM (CD56)-positive malignant lymphoma. 7512851 1993
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Phenotypic and genotypic studies revealed that the lymphoma is originated from either NK- or γδ T-cell, both of which express CD56. 31041299 2019
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Described for the first time in 1994 as CD4+ cutaneous lymphoma with high expression of CD56, BPDCN has been known previously with various names such as blastic natural killer (NK) leukemia/lymphoma, agranular CD4+ CD56+ hematodermic neoplasm, and agranular CD4+ NK cell leukemia. 29237977 2018
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Agranular CD4+CD56+ blastic natural killer leukemia/lymphoma. 11401089 2001
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE This case demonstrated nasal cavity and cutaneous tumor infiltrates consistent with previously described CD3-negative, CD56-positive NK-cell lymphoma of the upper aerodigestive tract. 7530849 1994
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The expression of the neural cell adhesion molecule (NCAM) (CD56, NKH-1) is a rare phenomenon in malignant lymphoma. 7532919 1995