NCAM1, neural cell adhesion molecule 1, 4684

N. diseases: 445; N. variants: 34
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE CD2+, CD3-, CD56/NCAM+ malignant lymphoma with TCR beta gene rearrangement: a case report. 7485082 1995
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE NCAM (CD56)-positive malignant lymphoma. 7512851 1993
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Thus, EBV may play an etiologic role in these CD56-positive lymphomas. 7520016 1994
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE This case demonstrated nasal cavity and cutaneous tumor infiltrates consistent with previously described CD3-negative, CD56-positive NK-cell lymphoma of the upper aerodigestive tract. 7530849 1994
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The expression of the neural cell adhesion molecule (NCAM) (CD56, NKH-1) is a rare phenomenon in malignant lymphoma. 7532919 1995
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE CD5-CD56+ T-cell receptor silent peripheral T-cell lymphomas are natural killer cell lymphomas. 8608237 1996
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Expression of NCAM could be regarded as responsible, in part, for the extranodal localization of lymphoma cells; expression of CD56 also might contribute to the definition of a subset of CD30+ lymphomas with distinctive clinicopathologic features. 9261474 1997
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE In this study we analysed the cytogenetic findings of seven patients with CD56-positive putative NK cell lymphoma/leukaemia. 9326190 1997
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Five CD3- CD56+ lymphoma patients presenting with nodular lesions were identified among 180 immunophenotyped cutaneous lymphomas. 9470917 1997
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Fifty percent of MVLs express CD56, suggesting a role for adhesion molecules in the distribution of this lymphoma. 9521469 1998
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE We also studied the expression of these molecules in 92 other cases of T-cell and natural killer (NK) cell neoplasms; 18 anaplastic large cell lymphomas (ALCLs); 63 CD4+ PTCLs; 10 CD56+ nasal lymphomas; and 1 NK-cell leukemia. 9578080 1998
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The diagnosis of NK cell lymphoma was made on the basis of morphological and immunological characteristics (CD3-CD56+) found on skin biopsy of one of multiple skin nodules which subsequently developed in association with splenomegaly, thrombocytopenia and continuing neutropenia. 9869207 1998
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE We consider that blastoid NK cell lymphoma is an extremely aggressive subtype of CD56-positive lymphomas, and high-dose chemotherapy with peripheral blood stem cell rescue should be included for the choice of the treatment. 10048432 1999
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE We have studied 12 patients of varied ethnic backgrounds with CD56-positive lymphomas in the skin. 10328090 1999
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE This study indicates that chromosome aberrations in NK-cell lymphomas are restricted to the CD56+, CD3- and CD5- cell population and that NK-cell lymphomas are indeed derived from mature true NK cells and not from T lymphocytes. 10354139 1999
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Primary purely cutaneous CD56 + lymphomas have rarely been reported. 10583121 1999
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Coexistence of two distinct cell populations (CD56(+)TcRgammadelta(+) and CD56(+)TcRgammadelta(-)) in a case of aggressive CD56(+) lymphoma/leukemia. 10800166 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Four patients with cutaneous CD4+ and CD56+ lymphoma were studied. 10828627 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Thus, there seems to be a useful distinction between the classical NK/T type of nasal lymphoma (CD56+/n-cdk6+/CD44-/TcR-GR-) and PTL (CD56-/n-cdk6-/CD44+/TcR-GR+) involving the nasal region. 10879740 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE Seven retrospectively identified cases of lymphomas with co-expression of CD56 and CD30 presenting in the skin comprise this study. 10955685 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE The indolent behavior of this tumor indicates its similarity to other primary cutaneous CD30+ large cell lymphomas and its difference from other CD56+ lymphomas involving the skin, which often exhibit an aggressive clinical course. 11048978 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE When immunostained using paraffin embedded tissue, 6 upper aerodigestive lymphomas were negative for CD56 in which 4 cases lacked clonal TCR gene rearrangement. 11066052 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 AlteredExpression group BEFREE A rare form of putative natural killer (NK) cell lymphoma called blastic NK cell lymphoma appears to be clinicopathologically distinctive in showing a homogenous lymphoblast, variable expression of CD2, CD4, CD56 and TdT, negative for surface CD3, T-cell receptor antigen, CD16, CD34 and lack of association with Epstein-Barr virus (EBV). 11328295 2001
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE Agranular CD4+CD56+ blastic natural killer leukemia/lymphoma. 11401089 2001
CUI: C0024299
Disease: Lymphoma
Lymphoma
0.100 Biomarker group BEFREE We report 4 cases of lymphomas/leukemias with the unusual CD56/CD4 phenotype. 11488062 2001