ATM, ATM serine/threonine kinase, 472

N. diseases: 684; N. variants: 974
Disease: Differentiated Thyroid Gland Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.030 GeneticVariation disease BEFREE We assessed the contribution of polymorphisms at the 9q22.33 and 14q13.3 loci identified by GWAS, and within the DNA repair gene ATM, to the risk of differentiated thyroid cancer (DTC) in 177 cases and 275 matched controls from the native population. 25849217 2015
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.030 GeneticVariation disease BEFREE Overall, no association between DTC and the coding SNP D1853N (rs1801516) in ATM (OR per A Allele = 1.1, 95% CI: 0.7-1.7) was seen. 25879635 2015
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.030 GeneticVariation disease BEFREE A significant dose-response relationship was observed between the total number of risk alleles of ATM and DTC risk (P = 0.01). 22438227 2012