ATM, ATM serine/threonine kinase, 472

N. diseases: 684; N. variants: 974
Disease: Differentiated Thyroid Gland Carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801516
rs1801516
Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C1337013
Disease:
Differentiated Thyroid Gland Carcinoma 		0.010 GeneticVariation BEFREE Overall, no association between DTC and the coding SNP D1853N (rs1801516) in ATM (OR per A Allele = 1.1, 95% CI: 0.7-1.7) was seen. 25879635 2015
dbSNP: rs1800057
rs1800057
Entrez Id: 472
Gene Symbol: ATM
ATM
CUI: C1337013
Disease:
Differentiated Thyroid Gland Carcinoma 		0.010 GeneticVariation BEFREE Under a dominant model of inheritance, the G allele of ATM rs189037 exhibited a protective effect against DTC (adjusted OR = 0.8; 95% CI, 0.6-1.0; P = 0.04), and the G allele of rs1800057 was associated with increased risk of DTC (adjusted OR = 1.9; 95% CI, 1.1-3.1; P = 0.02). 22438227 2012
dbSNP: rs189037
rs189037
Entrez Id: 472;4863
Gene Symbol: ATM;NPAT
ATM;NPAT
CUI: C1337013
Disease:
Differentiated Thyroid Gland Carcinoma 		0.010 GeneticVariation BEFREE Under a dominant model of inheritance, the G allele of ATM rs189037 exhibited a protective effect against DTC (adjusted OR = 0.8; 95% CI, 0.6-1.0; P = 0.04), and the G allele of rs1800057 was associated with increased risk of DTC (adjusted OR = 1.9; 95% CI, 1.1-3.1; P = 0.02). 22438227 2012