|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The present study was carried out with an aim to evaluate the association between the genetic variants of lipoprotein lipase gene [HindIII (+/+)/HindIII (-/-)], multiple drug resistance gene (C3435T) and endothelial nitric oxide synthase gene (4a/4b) with clinical outcome including an increased risk of recurrent stroke or death in ischemic stroke patients on atorvastatin therapy.
|
22810051 |
2012 |
|
Cerebrovascular accident
|
0.400 |
Biomarker
|
group |
BEFREE |
Studies from the different ethnic regions of world have reported variable results on association of Apolioprotein E (APOE), Methylenetetrahydrofolate reductase (MTHFR), Endothelial Nitric Oxide Synthase (ENOS), Factor V Leiden (F5), Cytochrome P450 4F2 (CYP4F2), beta-fibrinogen and Phosphodiesterase 4D (PDE4D) gene in stroke.
|
24090469 |
2013 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
MatInspector) were applied to investigate the main variant consequences.Variants in vascular adhesion molecule-1 (VCAM1) gene promoter and endothelial nitric oxide synthase (NOS3) gene were significantly associated with higher degree of hemolysis and stroke events.
|
27814292 |
2016 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
A tendency toward an increased LAA stroke risk was significant in carriers with the eNOS Glu298Asp variant in conjunction with the G14713 A and T29107A polymorphisms of the Cav-1 (aOR = 2.03, P-trend = 0.002).
|
28346478 |
2017 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The phosphoinositide 3‑kinase membrane translocation of cerebral stroke rats pretreated with CPT at various concentrations were measured, as well as the phosphorylation of protein kinase B (AKT) and endothelial nitric oxide synthase (eNOS).
|
29152647 |
2017 |
|
Cerebrovascular accident
|
0.400 |
Therapeutic
|
group |
RGD |
The phosphoinositide 3‑kinase membrane translocation of cerebral stroke rats pretreated with CPT at various concentrations were measured, as well as the phosphorylation of protein kinase B (AKT) and endothelial nitric oxide synthase (eNOS).
|
29152647 |
2017 |
|
Cerebrovascular accident
|
0.400 |
Biomarker
|
group |
BEFREE |
The purpose of the present study was to assess the specific role of eNOS in cognitive performance after stroke.
|
29406402 |
2018 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We identified an exonic polymorphism in NOS3 (rs1799983, rs1799983" genes_norm="4846">p.Glu298Asp; p = 2.2E-8, odds ratio [OR] = 1.05, 95% confidence interval [CI] = 1.04-1.07) and variants in an intron of COL4A1 (rs9521634; p = 3.8E-8, OR = 1.04, 95% CI = 1.03-1.06) and near DYRK1A (rs720470; p = 6.1E-9, OR = 1.05, 95% CI = 1.03-1.07) at genome-wide significance for stroke.
|
30383316 |
2018 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide meta-analysis identifies 3 novel loci associated with stroke.
|
30383316 |
2018 |
|
Cerebrovascular accident
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We assessed the effects of glyceryl trinitrate (GTN) on hemodynamic parameters and these on outcome in participants in the ENOS trial (Efficacy of Nitric Oxide in Stroke).
|
30626285 |
2019 |
|
Cerebrovascular accident
|
0.400 |
AlteredExpression
|
group |
BEFREE |
However, the activity of the eNOS enzyme and the metabolism of major NO metabolite S-nitrosoglutathione (GSNO) are dysregulated after stroke, causing endothelial dysfunction.
|
31680031 |
2019 |