Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0494475
Disease: Tonic - clonic seizures
Tonic - clonic seizures 		0.300 Biomarker disease CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751056
Disease: Non-epileptic convulsion
Non-epileptic convulsion 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751110
Disease: Single Seizure
Single Seizure 		0.300 Biomarker disease CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751123
Disease: Atonic Absence Seizures
Atonic Absence Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751494
Disease: Convulsive Seizures
Convulsive Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751495
Disease: Seizures, Focal
Seizures, Focal 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C0751496
Disease: Seizures, Sensory
Seizures, Sensory 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C3495874
Disease: Nonepileptic Seizures
Nonepileptic Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C4048158
Disease: Convulsions
Convulsions 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C4316903
Disease: Absence Seizures
Absence Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C4317109
Disease: Epileptic Seizures
Epileptic Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C4317123
Disease: Myoclonic Seizures
Myoclonic Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C4505436
Disease: Generalized Absence Seizures
Generalized Absence Seizures 		0.300 Biomarker phenotype CTD_human Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. 19815072 2010
CUI: C1527348
Disease: Brain Hypoxia
Brain Hypoxia 		0.200 Biomarker phenotype RGD Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing. 18818385 2009
CUI: C0020507
Disease: Hyperplasia
Hyperplasia 		0.200 Biomarker phenotype RGD We explored AM, PAMP, and PAM expression as markers for NE hyperplasia in three rodent species (Fischer 344 rats, Syrian golden hamsters, and A/J mice) after a single intratracheal instillation of crystalline silica (quartz), which was previously found to induce different reactions in the three species. 11742033 2001
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.200 Biomarker disease RGD Primary rat pituitary cells cultures from hypo- and euthyroid rats in the presence of actinomycin D showed that hypothyroidism increased the half-life of PAM mRNA from 9-10 h to 15-17 h. Taken together, these data suggest that hypothyroidism induces PAM mRNA levels by increasing its stability in the cytoplasm. 8940376 1996
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.110 GeneticVariation disease GWASCAT A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. 28892059 2017
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.110 AlteredExpression disease BEFREE We report here the discovery and characterization of VU0418506, a novel mGlu4 PAM with activity in rodent PD models. 27441572 2016
CUI: C0005890
Disease: Body Height
Body Height 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0205682
Disease: Waist-Hip Ratio
Waist-Hip Ratio 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0424574
Disease: Duration of sleep
Duration of sleep 		0.100 GeneticVariation phenotype GWASCAT Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. 30804565 2019
CUI: C0424574
Disease: Duration of sleep
Duration of sleep 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates. 30846698 2019
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
CUI: C0429087
Disease: Electrocardiogram: P-R interval
Electrocardiogram: P-R interval 		0.100 GeneticVariation phenotype GWASCAT PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. 30046033 2018