|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
20881960 |
2010 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
|
28552196 |
2017 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Fasting blood glucose measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
|
23400010 |
2014 |
|
Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
20881960 |
2010 |
|
Adenocarcinoma Of Esophagus
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Because selenium-binding protein 1 (SELENBP1, SBP1, hSP56) has been shown to bind selenium covalently and selenium deficiency has been associated with esophageal adenocarcinoma (EAC), we examined its role in EAC development and its potential effect on chemosensitivity in the presence of selenium.
|
20332323 |
2010 |
|
Malignant Neoplasms
|
0.060 |
Biomarker
|
group |
BEFREE |
It has been reported that suppression of selenium‑binding protein 1 (SBP1) occurs in many human malignancies which is considered to play an important role in cancer development and progression.
|
23483240 |
2013 |
|
Neoplasm Metastasis
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
The Drg-1 gene suppresses tumor metastasis in prostate cancer.
|
12702552 |
2003 |
|
Neoplasm Metastasis
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
17Beta-estradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells.
|
16707596 |
2006 |
|
Neoplasm Metastasis
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models.
|
15184886 |
2004 |
|
Tumor Cell Invasion
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
Moreover, we used RBE, a human ICC cell line, to study the effects of SBP1 knockdown on ICC cell proliferation, migration and invasion.
|
30662608 |
2018 |
|
Tumor Cell Invasion
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
However, SBP1 did not influence the invasion, phagocytosis or intracellular survival of SS2.
|
29886087 |
2018 |
|
Malignant tumor of colon
|
0.040 |
Biomarker
|
disease |
BEFREE |
The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer.
|
17178897 |
2006 |
|
Malignant tumor of colon
|
0.040 |
Biomarker
|
disease |
BEFREE |
On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models.
|
15184886 |
2004 |
|
Malignant tumor of colon
|
0.040 |
Biomarker
|
disease |
BEFREE |
We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype.
|
10676663 |
2000 |
|
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Tumor tissue microarrays indicated that SBP1 was an independent risk factor for overall survival and disease recurrence; patients with lower SBP1 expression experienced shorter overall survival periods and higher rates of disease recurrence (P < 0.001).
|
22512980 |
2012 |
|
Colon Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype.
|
10676663 |
2000 |
|
Colon Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models.
|
15184886 |
2004 |
|
Colon Carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer.
|
17178897 |
2006 |
|
Secondary Neoplasm
|
0.040 |
Biomarker
|
group |
BEFREE |
On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models.
|
15184886 |
2004 |
|
Secondary Neoplasm
|
0.040 |
Biomarker
|
group |
BEFREE |
The Drg-1 gene suppresses tumor metastasis in prostate cancer.
|
12702552 |
2003 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
We have investigated protein kinase C (PKC) signaling, a putative differentiation-related and metastasis suppressor gene Cap43/NDRG1/Drg-1, and Y-box binding protein-1 (YB-1) to identify new molecular targeting for breast cancer.
|
18224398 |
2008 |
|
Malignant neoplasm of breast
|
0.030 |
Biomarker
|
disease |
BEFREE |
Together, our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer.
|
15184886 |
2004 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
We have investigated protein kinase C (PKC) signaling, a putative differentiation-related and metastasis suppressor gene Cap43/NDRG1/Drg-1, and Y-box binding protein-1 (YB-1) to identify new molecular targeting for breast cancer.
|
18224398 |
2008 |
|
Breast Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Together, our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer.
|
15184886 |
2004 |