|
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
GWASCAT |
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
|
30061737 |
2018 |
|
Atrial Fibrillation
|
0.400 |
GeneticVariation
|
disease |
GWASCAT |
Multi-ethnic genome-wide association study for atrial fibrillation.
|
29892015 |
2018 |
|
Atrial Fibrillation
|
0.400 |
Biomarker
|
disease |
CTD_human |
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
|
30061737 |
2018 |
|
Atrial Fibrillation
|
0.400 |
Biomarker
|
disease |
CTD_human |
Multi-ethnic genome-wide association study for atrial fibrillation.
|
29892015 |
2018 |
|
Malignant neoplasm of prostate
|
0.310 |
Biomarker
|
disease |
BEFREE |
Subclassification of pT2 prostate cancer is not a prognostic indicator of survival related outcomes after radical prostatectomy.
|
29307681 |
2018 |
|
Malignant neoplasm of prostate
|
0.310 |
Biomarker
|
disease |
CTD_human |
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
|
29662167 |
2018 |
|
Paroxysmal atrial fibrillation
|
0.300 |
Biomarker
|
disease |
CTD_human |
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
|
30061737 |
2018 |
|
Paroxysmal atrial fibrillation
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multi-ethnic genome-wide association study for atrial fibrillation.
|
29892015 |
2018 |
|
Acute Cerebrovascular Accidents
|
0.300 |
Biomarker
|
disease |
CTD_human |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
|
29531354 |
2018 |
|
Chromosome 1p36 Deletion Syndrome
|
0.200 |
Biomarker
|
disease |
MGD |
Our results showed that loss of Casz1 during mouse development led to heart defect including cardiac noncompaction and ventricular septal defect, which phenocopies 1p36 deletion syndrome related CHD.
|
25190801 |
2014 |
|
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Multiple breast cancer survival related genes were found in this gene set, including FOXR2, FOXD1, MTNR1B and SDC1.
|
30454048 |
2018 |
|
Breast Carcinoma
|
0.130 |
AlteredExpression
|
disease |
BEFREE |
A whole genome screening of the survival related gene expression patterns in breast cancer was studied.
|
26576432 |
2015 |
|
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor percent positive staining is not independently related to breast cancer survival after adjustment for other survival-related factors.
|
28825224 |
2017 |
|
Breast Carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
|
Varicosity
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Clinical and Genetic Determinants of Varicose Veins.
|
30566020 |
2018 |
|
Varicosity
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Varicose veins of lower extremities: Insights from the first large-scale genetic study.
|
30998689 |
2019 |
|
Varicosity
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Recent reports have suggested a reproducible association between the rs11121615 SNP, located within an intron of the castor zinc finger 1 (CASZ1) gene, and varicose veins.
|
31570750 |
2019 |
|
Alopecia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
|
30940143 |
2019 |
|
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
|
29531354 |
2018 |
|
Neuroblastoma
|
0.080 |
Biomarker
|
disease |
BEFREE |
Treatment of NB cell lines with the histone deacetylase inhibitor trichostatin A led to increased gene transcription of four of the 30 genes, ERRFI1 (MIG-6), PIK3CD, RBP7 (CRBPIV) and CASZ1, indicating that these genes could be affected by epigenetic downregulation in NBs.
|
17940511 |
2007 |
|
Neuroblastoma
|
0.080 |
AlteredExpression
|
disease |
BEFREE |
These data are consistent with CASZ1 being a critical modulator of neural cell development, and that somatically acquired disruption of normal CASZ1 expression contributes to the malignant phenotype of human NB.
|
21252912 |
2011 |
|
Neuroblastoma
|
0.080 |
AlteredExpression
|
disease |
BEFREE |
Castor zinc finger 1 (CASZ1) is a transcription factor, prominently known for its tumor suppression role in neuroblastoma and other cancers.
|
31481981 |
2019 |
|
Neuroblastoma
|
0.080 |
Biomarker
|
disease |
BEFREE |
We identified this role for EZH2 by examining the regulation of CASZ1, a recently identified NB tumor suppressor gene whose ectopic restoration inhibits NB cell growth and induces differentiation.
|
22068036 |
2012 |
|
Neuroblastoma
|
0.080 |
AlteredExpression
|
disease |
BEFREE |
CASZ1b and CASZ1a expression is coordinately upregulated by the differentiation agent Retinoic Acid, as well as agents that modify the epigenome in neural crest derived neuroblastoma cell lines.
|
21490919 |
2011 |