|
Cerebrovascular accident
|
0.440 |
Biomarker
|
group |
BEFREE |
However, work from neuroimaging research has suggested a role of the contralesional hemisphere in promoting recovery after stroke potentially through the ipsilateral uncrossed CST fibers descending to ipsilateral spinal segments.
|
28691140 |
2017 |
|
Cerebrovascular accident
|
0.440 |
Biomarker
|
group |
BEFREE |
CST Injury and LM1-RM1 rs-connectivity each individually correlate with motor outcome post-stroke, but less is understood about the relationship between these biomarkers.
|
29930399 |
2018 |
|
Cerebrovascular accident
|
0.440 |
Biomarker
|
group |
BEFREE |
This protocol may have practical application in testing CST integrity after stroke when paretic limb thresholds are high, by increasing the likelihood of eliciting a MEP.
|
27840187 |
2017 |
|
Cerebrovascular accident
|
0.440 |
Biomarker
|
group |
BEFREE |
Following lesion masking and correction for multiple comparisons, relative increases in FW were found for the stroke group in large portions of the M1-CST and PMd-CST in the lesioned hemisphere.
|
28590584 |
2017 |
|
Malignant neoplasm of prostate
|
0.310 |
Biomarker
|
disease |
BEFREE |
Subclassification of pT2 prostate cancer is not a prognostic indicator of survival related outcomes after radical prostatectomy.
|
29307681 |
2018 |
|
Cardiovascular Diseases
|
0.130 |
GeneticVariation
|
group |
BEFREE |
Cortistatin (CST), a newly discovered biological peptide, has been acknowledged for its protective effects against cardiovascular diseases.
|
31807542 |
2019 |
|
Cardiovascular Diseases
|
0.130 |
Biomarker
|
group |
BEFREE |
Therefore, we reviewed the cardiovascular effects of CST in the heart and blood vessels, which will help to understand the role of CST and its receptors in the pathogenesis of cardiovascular diseases, and highlight novel strategies and targets for the prevention and treatment of cardiovascular diseases.
|
31555545 |
2019 |
|
Cardiovascular Diseases
|
0.130 |
GeneticVariation
|
group |
BEFREE |
In conclusion, the CST Ser-364 allele may increase the risk for cardiovascular diseases in Japanese population.
|
26211667 |
2015 |
|
Hypertensive disease
|
0.130 |
GeneticVariation
|
group |
BEFREE |
Here, we report case-control studies in 2 geographically/ethnically distinct Indian populations (n≈4000) that showed association of the naturally-occurring human CST-Gly364Ser variant with increased risk for hypertension (age-adjusted odds ratios: 1.483; P=0.009 and 2.951; P=0.005).
|
27324226 |
2016 |
|
Hypertensive disease
|
0.130 |
Biomarker
|
group |
BEFREE |
Indeed, additional studies have revealed that the pro-inflammatory PST influences insulin sensitivity and glucose tolerance, whereas CST alleviates adiposity and hypertension.
|
28228748 |
2017 |
|
Hypertensive disease
|
0.130 |
Biomarker
|
group |
BEFREE |
Consistent with human findings, the lack of CST in CgA knockout (Chga-KO) mice eventuates in the development of hypertension and supplementation of CST to Chga-KO mice restores blood pressure, implicating CST as a key player in regulating hypertension.
|
28443506 |
2018 |
|
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Multiple breast cancer survival related genes were found in this gene set, including FOXR2, FOXD1, MTNR1B and SDC1.
|
30454048 |
2018 |
|
Breast Carcinoma
|
0.130 |
AlteredExpression
|
disease |
BEFREE |
A whole genome screening of the survival related gene expression patterns in breast cancer was studied.
|
26576432 |
2015 |
|
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor percent positive staining is not independently related to breast cancer survival after adjustment for other survival-related factors.
|
28825224 |
2017 |
|
Varicosity
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Recent reports have suggested a reproducible association between the rs11121615 SNP, located within an intron of the castor zinc finger 1 (CASZ1) gene, and varicose veins.
|
31570750 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In contrast to nonobese diabetic severe combined immunodeficient <i>Il2rg</i><sup>-/-</sup> (NSG) mice, human NK cells in SRG-15 mice did not require preactivation but infiltrated a Burkitt's lymphoma xenograft and efficiently inhibited tumor growth following treatment with the therapeutic antibody rituximab.
|
29078283 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In neuroblastoma tumors, loss of CASZ1 is associated with poor prognosis and restoration of CASZ1 function suppresses neuroblastoma tumorigenicity.
|
22331471 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression.
|
21252912 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
ECRF is associated with poorer long-term survival related to a reduced utilisation of neoadjuvant chemoradiotherapy and an increased incidence of tumour margin involvement at surgery.
|
28236769 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
There remains a paucity of literature on survival related to pediatric appendiceal tumors.
|
29656783 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In survival analysis, a low expression of CASZ1 was significantly correlated with unfavorable progression-free survival (PFS) (<i>p</i> < 0.001), overall survival (OS) (<i>p</i> < 0.001), and cancer-specific survival (CSS) (<i>p</i> < 0.001) and was an independent prognostic factor for PFS and CSS in multivariate analysis adjusted for tumor size, WHO/ISUP grade, T category, N category, and M category.
|
31481981 |
2019 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Of particular note is that one of the genes involved is the recently described novel tumor suppressor gene castor zinc finger 1.
|
22262398 |
2012 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our previous study showed that full length CASZ1 (CASZ1a) functions to suppress growth in neuroblastoma tumor.
|
21490919 |
2011 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We identify hundreds of microRNAs whose direction and/or significance of tumor-normal differential expression is associated with one or more lifestyle, tumor molecular phenotype, or survival-related factors.
|
29084506 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We examined patient survival related to tumor locations, surgical treatment, postoperative course, radiotherapy, chemotherapy, patient age, GBM recurrence, imaging characteristics, serum, and molecular markers.
|
23614654 |
2013 |