CASZ1, castor zinc finger 1, 54897

N. diseases: 132; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 Biomarker group BEFREE Cancer invasiveness appeared to be a key reason for the poor survival related to highly expressed Romo1. 28472059 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 Biomarker group BEFREE Cancer invasiveness appeared to be a key reason for the poor survival related to highly expressed Romo1. 28472059 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 AlteredExpression group BEFREE CASZ1 is expressed in a number of human tumors and localizes to a chromosomal region frequently lost in tumors of neuroectodermal origin. 16631614 2006
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression. 21252912 2011
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE CASZ1 functions as a tumor suppressor in NB; here we sought to determine how loss of CASZ1 contributes to cell cycle dysregulation in NB. 23892435 2013
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.080 Biomarker disease BEFREE CASZ1 restoration in NB cells delays NB cell cycle progression. 23892435 2013
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.080 Biomarker disease BEFREE CASZ1 restoration in NB cells delays NB cell cycle progression. 23892435 2013
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		0.080 Biomarker disease BEFREE CASZ1 restoration in NB cells delays NB cell cycle progression. 23892435 2013
CUI: C0152021
Disease: Congenital heart disease
Congenital heart disease 		0.010 GeneticVariation group BEFREE CASZ1 loss-of-function mutation associated with congenital heart disease. 27693370 2016
CUI: C0340427
Disease: Familial dilated cardiomyopathy
Familial dilated cardiomyopathy 		0.010 GeneticVariation disease BEFREE CASZ1 loss-of-function mutation contributes to familial dilated cardiomyopathy. 28099117 2017
CUI: C0014070
Disease: Encephalomyelitis
Encephalomyelitis 		0.010 Biomarker disease BEFREE Casz1 deficiency in CD4<sup>+</sup> T cells lowers susceptibility to experimental autoimmune encephalomyelitis, consistent with the reduced frequency of Th17 cells, despite an increase in Th1 cells in mice. 29467767 2018
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.040 Biomarker group BEFREE Castor zinc finger 1 (CASZ1) plays critical roles in various biological processes and pathologic conditions, including cancer. 29506567 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 Biomarker group BEFREE Castor zinc finger 1 (CASZ1) plays critical roles in various biological processes and pathologic conditions, including cancer. 29506567 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.010 Biomarker disease BEFREE CST may be a potential agent or supplement against IAV infection. 29783993 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.440 Biomarker group BEFREE CST Injury and LM1-RM1 rs-connectivity each individually correlate with motor outcome post-stroke, but less is understood about the relationship between these biomarkers. 29930399 2018
CUI: C0011847
Disease: Diabetes
Diabetes 		0.010 Biomarker disease BEFREE CST could reduce inflammation in various mouse models for diabetes, colitis and atherosclerosis. 30337922 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.010 Biomarker group BEFREE CST could reduce inflammation in various mouse models for diabetes, colitis and atherosclerosis. 30337922 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.030 Biomarker disease BEFREE CST could reduce inflammation in various mouse models for diabetes, colitis and atherosclerosis. 30337922 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 Biomarker disease BEFREE CST could reduce inflammation in various mouse models for diabetes, colitis and atherosclerosis. 30337922 2018
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.010 Biomarker disease BEFREE CST may be a neuropeptide that plays a role in the pathogenesis of BD. 31314641 2019
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.080 AlteredExpression disease BEFREE Castor zinc finger 1 (CASZ1) is a transcription factor, prominently known for its tumor suppression role in neuroblastoma and other cancers. 31481981 2019
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.080 AlteredExpression disease BEFREE Castor zinc finger 1 (CASZ1) is a transcription factor, prominently known for its tumor suppression role in neuroblastoma and other cancers. 31481981 2019
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		0.080 AlteredExpression disease BEFREE Castor zinc finger 1 (CASZ1) is a transcription factor, prominently known for its tumor suppression role in neuroblastoma and other cancers. 31481981 2019
CUI: C0017654
Disease: Glomerular Filtration Rate
Glomerular Filtration Rate 		0.100 GeneticVariation phenotype GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 AlteredExpression disease BEFREE A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer. 29867125 2018