PTX3, pentraxin 3, 5806

N. diseases: 296; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.310 AlteredExpression disease BEFREE Differential expression of pentraxin 3 in fibroblasts from patients with major depression. 14603263 2004
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.310 Biomarker disease PSYGENET Differential expression of pentraxin 3 in fibroblasts from patients with major depression. 14603263 2004
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.310 AlteredExpression phenotype BEFREE The densitometric analysis of slot blots showed that the mean steady-state mRNA level of PTX3 was 3.5-fold higher in the melancholic group as compared to that in normal controls and in nonmelancholic depressives (n=8, all groups). 14603263 2004
CUI: C0344315
Disease: Depressed mood
Depressed mood
0.310 Biomarker phenotype PSYGENET The densitometric analysis of slot blots showed that the mean steady-state mRNA level of PTX3 was 3.5-fold higher in the melancholic group as compared to that in normal controls and in nonmelancholic depressives (n=8, all groups). 14603263 2004
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.310 Biomarker disease PSYGENET Differential expression of pentraxin 3 in fibroblasts from patients with major depression. 14603263 2004
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.310 AlteredExpression disease BEFREE Differential expression of pentraxin 3 in fibroblasts from patients with major depression. 14603263 2004
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.300 Biomarker disease CTD_human Maximal plasma PTX3 level was significantly higher in the pulmonary fibrosis group, and plasma PTX3 was significantly increased throughout hemoperfusion therapy (p<0.01). 22210019 2012
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing
0.300 Biomarker disease CTD_human The role of pentraxin-3 as a prognostic biomarker in paraquat poisoning. 22210019 2012
CUI: C0037274
Disease: Dermatologic disorders
Dermatologic disorders
0.300 Biomarker group CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0274861
Disease: Arsenic Poisoning, Inorganic
Arsenic Poisoning, Inorganic
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
Nervous System, Organic Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0311375
Disease: Arsenic Poisoning
Arsenic Poisoning
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751851
Disease: Arsenic Encephalopathy
Arsenic Encephalopathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0751852
Disease: Arsenic Induced Polyneuropathy
Arsenic Induced Polyneuropathy
0.300 Biomarker disease CTD_human Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population. 16835338 2006
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 AlteredExpression disease BEFREE We investigated whether the plasma PTX3 level was associated with progression of joint destruction and subclinical atherosclerosis in RA patients.<b>Methods:</b> Plasma PTX3 levels were measured in 72 women with RA and 80 female control subjects. 31615315 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.100 Biomarker disease BEFREE The circulating PTX3 level was inversely associated with metabolic syndrome, overweight/obesity, and parameters of dyslipidemia, suggesting a cardioprotective role of PTX3 in atherosclerosis. 30674758 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 AlteredExpression disease BEFREE We investigated whether the plasma PTX3 level was associated with progression of joint destruction and subclinical atherosclerosis in RA patients.<b>Methods:</b> Plasma PTX3 levels were measured in 72 women with RA and 80 female control subjects. 31615315 2019
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.100 Biomarker disease BEFREE The circulating PTX3 level was inversely associated with metabolic syndrome, overweight/obesity, and parameters of dyslipidemia, suggesting a cardioprotective role of PTX3 in atherosclerosis. 30674758 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker group BEFREE Pentraxin 3 (PTX3) and nuclear factor-like 2 (Nrf2) are known to induce tumor progression in certain malignancies but act as tumor suppressors in other human neoplasms. 30942197 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker group BEFREE The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer. 31019517 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker group BEFREE PTX3, a member of the long pentraxin subfamily, associated with innate immunity is indispensable for resistance to some cancer. 30628067 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker group BEFREE Long pentraxin‑3 (PTX3) is an inflammatory molecule related to cancer proliferation, invasion, and metastasis. 30483742 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 GeneticVariation group BEFREE However, the clinical significance of <i>PTX3</i> polymorphisms in oral cancer and their correlation with the risk of cancer are still unclear. 31334115 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE PTX3 has been investigated in several clinical settings as possible biomarker of CVD. 31057548 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE PTX3 and hs-CRP may be related to the pathogenesis of GDM, and they are significantly increased in the second trimester, which provides a new idea for early prevention and treatment of GDM and risk prediction of long-term cardiovascular diseases. 31721795 2019