|
Acute lymphocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Specifically, c-MYB (P </= 0.04) was significantly increased in ALL in the total fraction, whilst HOXA9 (P </= 0.19) and cystatin c (P </= 0.01) were increased in AML in the CD34(+) and CD34(-) fractions, respectively. c-MYB, hSNF2, RBAP48, HKRT-1, LYN, CD33, Adipsin and HOXA9 were increased in AML compared with remission AML, indicating an ability to determine disease activity.
|
16029452 |
2005 |
|
Adult Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.
|
26972001 |
2016 |
|
Amnesia
|
0.040 |
Biomarker
|
disease |
BEFREE |
Rbbp4 (involved in age-related memory loss) was increased in tibia callus after ovariectomy.
|
28860177 |
2018 |
|
Amnesia
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Up-regulation of RbAp48 in the DG of aged wild-type mice ameliorated age-related hippocampus-based memory loss and age-related abnormalities in histone acetylation.
|
23986399 |
2013 |
|
Amnesia
|
0.040 |
Biomarker
|
disease |
BEFREE |
We have previously shown that the histone-binding protein RbAp48/Rbbp4 is a molecular determinant of Age-Related Memory Loss.
|
30355501 |
2018 |
|
Amnesia
|
0.040 |
Biomarker
|
disease |
BEFREE |
The epigenetic factor LIN-53 (RBBP4/7) associates with different chromatin-regulating complexes to safeguard cell identities in Caenorhabditis elegans as well as mammals, and has a role in preventing memory loss and premature aging in humans.
|
31397537 |
2019 |
|
Brain Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Our study provides new insight into the epigenetic processes that might drive pathogenesis in RB1 brain tumors, and identifies Rbbp4 and its associated chromatin remodeling complexes as potential target pathways to induce apoptosis in RB1 mutant brain cancer cells.This article has an associated First Person interview with the first author of the paper.
|
29914980 |
2018 |
|
Carcinogenesis
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Blocking the interaction between ARMC12 and RBBP4 by cell-penetrating inhibitory peptide activates the downstream gene expression and suppresses the tumorigenesis and aggressiveness of NB cells.
|
30026490 |
2018 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
This promoting effect of hPuf-A in tumorigenesis might be correlated with the regulation of its associated mRNAs, such as RbAp48 and DDX3.
|
23625657 |
2013 |
|
Carcinogenesis
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
Globally, RBBP4 positively and negatively regulates genes involved in critical cellular functions including tumorigenesis.
|
26972001 |
2016 |
|
Carcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Immunohistochemical analysis of normal and pathological human thyroid specimens confirmed that RbAp48 is strongly overexpressed in primary human carcinomas.
|
17244783 |
2007 |
|
Central neuroblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Both ARMC12 and RBBP4 are upregulated in NB tissues, and are associated with unfavorable outcome of patients.
|
30026490 |
2018 |
|
cervical cancer
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In brief, RbAp48, previously unknown in cervical carcinogenesis, was isolated in a global screen and identified as a critical mediator controlling the transforming activity of HPV16 in cervical cancer.
|
17616526 |
2007 |
|
cervical cancer
|
0.030 |
Biomarker
|
disease |
BEFREE |
RbAp48 may be a potential target to improve the results of radiation therapy for patients with cervical cancer.
|
23756179 |
2013 |
|
cervical cancer
|
0.030 |
Biomarker
|
disease |
BEFREE |
RbAp48 may be a therapeutic target that may help to improve the treatment of cervical cancer.
|
28138695 |
2017 |
|
Cervical Intraepithelial Neoplasia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Among them, retinoblastoma-binding protein 4 (RbAp48) was selected, and its differentiation expression was verified with both additional cervical cancer-derived cell lines and human tissues of cervical intraepithelial neoplasia and cervical cancer.
|
17616526 |
2007 |
|
Cervix carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
RbAp48 may be a potential target to improve the results of radiation therapy for patients with cervical cancer.
|
23756179 |
2013 |
|
Cervix carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In brief, RbAp48, previously unknown in cervical carcinogenesis, was isolated in a global screen and identified as a critical mediator controlling the transforming activity of HPV16 in cervical cancer.
|
17616526 |
2007 |
|
Cervix carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
RbAp48 may be a therapeutic target that may help to improve the treatment of cervical cancer.
|
28138695 |
2017 |
|
Childhood Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.
|
26972001 |
2016 |
|
Childhood Neuroblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Both ARMC12 and RBBP4 are upregulated in NB tissues, and are associated with unfavorable outcome of patients.
|
30026490 |
2018 |
|
Chronic kidney disease stage 5
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, Lasso logistic regression was conducted to identify five final genes, namely, CNOT8, MST4, PPP2CB, PCSK7 and RBBP4 that are differentially expressed and associated with ESKD.
|
31464346 |
2019 |
|
Colon Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
RBBP4 was up-regulated in the colon cancer tissues compared with the para-colon cancer tissues.
|
31501018 |
2019 |
|
Glioblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.
|
26972001 |
2016 |
|
Glioblastoma Multiforme
|
0.010 |
Biomarker
|
disease |
BEFREE |
Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins.
|
26972001 |
2016 |