|
Hidradenitis Suppurativa
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
SAA and CRP levels and ESR were significantly associated with Hurley staging in patients with HS (P = 0.03, P = 0.003, P = 0.02).
|
31729595 |
2020 |
|
Aneurysm of popliteal artery
|
0.010 |
Biomarker
|
disease |
BEFREE |
A high prevalence of PA among subjects with screening detected AAA and SAA was found.
|
31757587 |
2020 |
|
Appendicitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Plasma levels of IL-6, CRP, MCP-1, PCT, and SAA were significantly different in children with AA compared to those with NAAP (<i>p</i> < 0.001).
|
30918467 |
2019 |
|
Colorectal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of SAA by hepatocytes also occurs in patients with pancreatic and colorectal cancers that have metastasized to the liver, and many patients with locally advanced and metastatic disease show increases in circulating SAA.
|
30842658 |
2019 |
|
Hypertensive disease
|
0.010 |
Biomarker
|
group |
BEFREE |
Despite the high burden of hypertension in SAA, strategies to improve awareness, diagnosis, and management are inadequate.
|
31451940 |
2019 |
|
Phenylketonurias
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The inflammatory markers C-reactive protein and serum amyloid A protein and the serum oxidative stress marker malondialdehyde were significantly higher in patients with PKU.
|
31492166 |
2019 |
|
Pneumonia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Regarding biomarkers, MR-proADM at 24 h (P = 0.04) and both suPAR and SAA at 48 h (P = 0.036 and P = 0.057) were associated with pneumonia.
|
31365180 |
2019 |
|
Retinopathy of Prematurity
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Specifically, CpG methylation in the serum amyloid A SAA1 and SAA2, brain-derived neurotrophic factor (BDNF), myeloperoxidase (MPO), C-reactive protein (CRP), angiopoietin 1 (ANGPT1), and tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) genes was associated with a lower risk of prethreshold ROP.
|
31266060 |
2019 |
|
Tuberculosis, Meningeal
|
0.010 |
Biomarker
|
disease |
BEFREE |
A modified version of the adult 7-marker biosignature in which transthyretin was replaced by NCAM1, diagnosed TBM in children with AUC of 0.80 (95% CI, 0.67-0.92), sensitivity of 73.9% (95% CI, 51.6-89.8%) and specificity of 66.7% (95% CI, 44.7-84.4%), with the other six proteins in the signature (CRP, IFN-γ, IP-10, CFH, Apo-A1, and SAA) only achieving and AUC of 0.75 (95% CI, 0.61-0.90) when used in combination.
|
31612118 |
2019 |
|
Acute appendicitis NOS (disorder)
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Plasma levels of IL-6, CRP, MCP-1, PCT, and SAA were significantly different in children with AA compared to those with NAAP (<i>p</i> < 0.001).
|
30918467 |
2019 |
|
Allergic asthma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Omalizumab is a recombinant monoclonal anti-IgE antibody approved in the US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma [SAA] in Europe).
|
30763137 |
2019 |
|
Neurologic Symptoms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
After introducing TCZ, her neurological symptoms and MRI findings gradually improved.SAA levels remained low.
|
31277158 |
2019 |
|
acute aortic dissection
|
0.010 |
Biomarker
|
disease |
BEFREE |
Serum amyloid a protein as a potential biomarker in predicting acute onset and association with in-hospital death in acute aortic dissection.
|
31810459 |
2019 |
|
Malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Significantly higher blood concentrations of sPD-L1 and SAA1 were noted in lung cancer patients compared with a healthy control group.
|
31156344 |
2019 |
|
Carcinogenesis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
During early pancreatic tumorigenesis in mice, hepatocytes show activation of signal transducer and activator of transcription 3 (STAT3) signalling and increased production of serum amyloid A1 and A2 (referred to collectively as SAA).
|
30842658 |
2019 |
|
Carcinoma of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Significantly higher blood concentrations of sPD-L1 and SAA1 were noted in lung cancer patients compared with a healthy control group.
|
31156344 |
2019 |
|
Acute anterior uveitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
To investigate the association between serum amyloid A (SAA) protein and the clinical features of acute anterior uveitis (AAU), and to evaluate the disease activity and treatment effect in relation to SAA levels.
|
31844164 |
2019 |
|
Primary malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Significantly higher blood concentrations of sPD-L1 and SAA1 were noted in lung cancer patients compared with a healthy control group.
|
31156344 |
2019 |
|
Pneumonia, Ventilator-Associated
|
0.010 |
Biomarker
|
disease |
BEFREE |
Diagnostic Efficacy of Serum Amyloid A Protein and Soluble Intercellular Adhesion Molecule 1 in Pediatric Ventilator-Associated Pneumonia.
|
28403662 |
2019 |
|
Triple Negative Breast Neoplasms
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among the SAA receptors, <i>TLR1</i> and <i>TLR2</i> were highly expressed in TNBC.
|
30728901 |
2019 |
|
Luminal B Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Triple-negative breast cancer (TNBC) subtype highly expressed <i>SAA1/2</i> compared to HER2, luminal A (LA) and luminal B (LB) subtypes.
|
30728901 |
2019 |
|
Immunosuppression
|
0.010 |
Biomarker
|
disease |
BEFREE |
We report the successful treatment of two patients with SAA, aged 15 and 24 months, with autologous cord blood combined with immunosuppression.
|
30407702 |
2019 |
|
Triple-Negative Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among the SAA receptors, <i>TLR1</i> and <i>TLR2</i> were highly expressed in TNBC.
|
30728901 |
2019 |
|
Adenocarcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Clopidogrel prevented the early elevation of the plasma SAA protein level, decreased colitis severity, and delayed the formation of dysplastic lesions and adenocarcinoma.
|
29369476 |
2018 |
|
Atrial Septal Defects
|
0.010 |
Biomarker
|
group |
BEFREE |
ASD (N = 36) assessed at age 10 years is associated with recurrent top quartile concentrations of inflammation-related proteins during the first post-natal month (e.g., SAA odds ratio (OR); 95% confidence interval (CI): 2.5; 1.2-5.3) and IL-6 (OR; 95% CI: 2.6; 1.03-6.4)).
|
29884819 |
2018 |