ST14, suppression of tumorigenicity 14, 6768

N. diseases: 170; N. variants: 9
Disease: Crohn Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.020 AlteredExpression disease BEFREE Both matriptase and prostasin are significantly down-regulated in colonic tissues from human subjects with active ulcerative colitis or Crohn's disease, implicating the loss of this barrier-protective protease pathway in the pathogenesis of irritable bowel disease. 28490634 2017
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.020 AlteredExpression disease BEFREE Matriptase protein and ST14 mRNA levels are significantly downregulated in inflamed colonic tissues from Crohn's disease and ulcerative colitis patients. 22081509 2012