|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The prevalence of thyroid disorders in women was low, but Tg was elevated in 13% of the pregnant women.
|
30843107 |
2020 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
To address the first question, we analyzed GWAS data from a general population and its two subpopulations, one with thyroid disease and/or abnormal thyroid function tests and the other without, in which circulating Tg levels had been measured.
|
31421134 |
2020 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
We calculated the rate of these thyroid diseases and positive antibodies to thyroglobulin (ATGAb), thyroid peroxidase (TPOAb) in SLE patients grouped by the presence of overlap syndrome and anti-dsDNA antibody.
|
28712818 |
2019 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thyroglobulin antibody (TG-Ab) and thyroid peroxidase antibody (TPO-Ab) are cornerstone biomarkers for autoimmune thyroid diseases, and establishment of appropriate thresholds is crucial for physicians to appropriately interpret test results.
|
31476287 |
2019 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Meta-analysis of studies eligible for quantitative synthesis was performed to estimate pooled odds ratios of thyroid antibodies; thyroid peroxidase antibody (TPO-Ab) and thyroglobulin antibody (TG-Ab), diagnosed thyroid diseases and serological thyroid dysfunctions.
|
31197884 |
2019 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The prevalence of thyroid disease (TD) (OR: 3.932; 95% CI: 2.230-6.933), autoimmune TD (OR: 5.879; 95% CI: 2.682-12.885), anti-thyroperoxidase (TPO) antibody (OR: 3.838; 95% CI: 2.968-4.963), and anti-thyroglobulin antibody (OR: 3.513; 95% CI: 2.346-5.260) was significantly higher in vitiligo patients than in controls.
|
30698146 |
2018 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In Kenya and Tanzania: (i) median UIC was well above thresholds for adequate iodine nutrition in all groups and exceeded the threshold for excess iodine intake in SAC; (ii) iodine concentrations >40 mg of iodine/kg were found in approximately 55% of household salt samples; (iii) iodine concentrations ≥10 μg/L were detected in 9% of drinking water samples; (iv) Tg was elevated in all population groups, but the prevalence of thyroid disorders was negligible, except that 5-12% of women of reproductive age had subclinical hyperthyroidism and 10-15% of PW were hypothyroxinemic.
|
30019625 |
2018 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The serum Tg level reflects abnormal thyroid function and is a sensitive functional biomarker of iodine nutrition status.
|
28756810 |
2017 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Mean and median serum Tg levels were higher among participants with abnormal thyroid structure/function.
|
28505591 |
2017 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thyroglobulin (TG) is known to be associated with autoimmune thyroid disorders and thus exon 33 (E33) SNP in TG was investigated.
|
26963610 |
2016 |
|
Thyroid Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Mutations of the thyroglobulin gene and its relevance to thyroid disorders.
|
19633549 |
2009 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Our objective was to examine the prevalence of pendrin antibodies in autoimmune thyroid diseases and compare with that of thyroglobulin, thyroperoxidase, TSH receptor, and sodium iodide symporter antibodies.
|
19050049 |
2009 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Analysis of the quantification of Tg mRNA from 20 healthy subjects and 47 subjects with thyroid disease was carried out by real-time PCR.
|
18243140 |
2008 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Thyroglobulin mRNA expression in peripheral blood lymphocytes of healthy subjects and patients with thyroid disease.
|
18243140 |
2008 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
LHGDN |
Dissecting genetic heterogeneity in autoimmune thyroid diseases by subset analysis.
|
17644307 |
2007 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Our results suggest that the molecular detection of circulating thyroid cancer cells by RT-PCR for TSHR/Tg mRNA complements FNA cytology in the preoperative differentiation of benign from malignant thyroid disease and their combined use may save unnecessary surgeries.
|
15687333 |
2005 |
|
Thyroid Diseases
|
0.100 |
GeneticVariation
|
group |
LHGDN |
Common allelic variants of exons 10, 12, and 33 of the thyroglobulin gene are not associated with autoimmune thyroid disease in the United Kingdom.
|
15579800 |
2004 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Detection of thyrotropin-receptor messenger ribonucleic acid (mRNA) and thyroglobulin mRNA transcripts in peripheral blood of patients with thyroid disease: sensitive and specific markers for thyroid cancer.
|
15292293 |
2004 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
These results suggest that detection of Tg mRNA in blood is a more sensitive marker for metastatic thyroid disease than Tg immunoassay, and appears to be unaffected by the presence of circulating anti-Tg antibodies.
|
12782763 |
2003 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We compared three methods of blood collection and RNA extraction, and quantified Tg mRNA (by real time RT-PCR) in the peripheral blood of a) probands without thyroid disease (n=42), patients with b) thyroid autonomy (n=15), c) Graves' disease (n=22), d) euthyroid goiter (n=6), and in DTC-patients after thyroidectomy and radioiodine therapy e) with (n=16) and f) without (n=37) metastasis.
|
12444888 |
2002 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The aim of our study was to evaluate Tg content in the thyroids and Tg concentrations in the serum of 108 patients suffering from benign or malignant thyroid disorders.
|
12022704 |
2002 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases.
|
11788684 |
2002 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Serum thyroglobulin measurement has greatly facilitated the clinical management of patients with differentiated thyroid cancer and a variety of other thyroid disorders.
|
11444170 |
2001 |
|
Thyroid Diseases
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Thyroglobulin messenger ribonucleic acid levels in the peripheral blood of children with benign and malignant thyroid disease.
|
11228272 |
2001 |
|
Thyroid Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Detection of mRNA transcripts for thyroglobulin (TG), thyroid peroxidase (TPO) and RET/PTC1 in the peripheral blood of patients with thyroid disease.
|
9508203 |
1998 |