Squamous cell carcinoma of lung
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
Glioma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we investigated whether cALLa expressed on glioma cell lines is active NEP.
|
2531122 |
1989 |
leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The amino acid sequence of cALLa is identical to that of neutral endopeptidase (NEP,E.C.3.4.24.11), and cALLa expressed on leukemia and melanoma cell lines is enzymatically active NEP.
|
2531122 |
1989 |
Common acute lymphoblastic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
The common acute lymphoblastic leukemia antigen (CALLA) is a 749-amino acid type II integral membrane protein that has been identified recently as the neutral endopeptidase 24.11 [NEP (EC 3.4.24.11)].
|
2528730 |
1989 |
Childhood Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The amino acid sequence of cALLa is identical to that of neutral endopeptidase (NEP,E.C.3.4.24.11), and cALLa expressed on leukemia and melanoma cell lines is enzymatically active NEP.
|
2531122 |
1989 |
Carcinoma, Ovarian Epithelial
|
0.040 |
Biomarker
|
disease |
BEFREE |
A protein receptor tyrosine kinase (RTK 6) has been isolated from a complementary DNA library of SKOV-3, an epithelial ovarian cancer cell line, using a polymerase chain reaction (PCR)-mediated approach.
|
7848919 |
1994 |
Epithelial ovarian cancer
|
0.030 |
Biomarker
|
disease |
BEFREE |
A protein receptor tyrosine kinase (RTK 6) has been isolated from a complementary DNA library of SKOV-3, an epithelial ovarian cancer cell line, using a polymerase chain reaction (PCR)-mediated approach.
|
7848919 |
1994 |
Carcinoma, Ovarian Epithelial
|
0.040 |
Biomarker
|
disease |
BEFREE |
A protein receptor tyrosine kinase (EDDR1) has been isolated from a complementary DNA library of SKOV-3, an epithelial ovarian cancer cell line.
|
7789998 |
1995 |
Epithelial ovarian cancer
|
0.030 |
Biomarker
|
disease |
BEFREE |
A protein receptor tyrosine kinase (EDDR1) has been isolated from a complementary DNA library of SKOV-3, an epithelial ovarian cancer cell line.
|
7789998 |
1995 |
Mammary Neoplasms
|
0.040 |
AlteredExpression
|
group |
BEFREE |
Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines.
|
8622863 |
1996 |
Malignant neoplasm of urinary bladder
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The results indicated that TRK-E and Arg kinases were more abundantly expressed than several other kinases in bladder cancer.
|
9252693 |
1997 |
Bladder Neoplasm
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The results indicated that TRK-E and Arg kinases were more abundantly expressed than several other kinases in bladder cancer.
|
9252693 |
1997 |
Carcinoma of bladder
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The results indicated that TRK-E and Arg kinases were more abundantly expressed than several other kinases in bladder cancer.
|
9252693 |
1997 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
All the high-grade primary brain and metastatic brain tumors showed unequivocal, intense DDR1 expression within the majority of tumor cells, whereas expression was not observed in hyperplastic tumor blood vessels, normal brain blood vessels, inflammatory cells, or in the normal brain tissue that surrounded the tumor.
|
11126911 |
2000 |
Glioblastoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
By use of a digoxigenin-labeled DDR1 riboprobe, we investigated the expression of DDR1 messenger ribonucleic acid in a prospective series of 30 resected human primary and metastatic brain neoplasms, nonneoplastic human brain, and mouse embryonic brain, as well as a mouse glioblastoma model, by in situ hybridization.
|
11126911 |
2000 |
Glioblastoma Multiforme
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
By use of a digoxigenin-labeled DDR1 riboprobe, we investigated the expression of DDR1 messenger ribonucleic acid in a prospective series of 30 resected human primary and metastatic brain neoplasms, nonneoplastic human brain, and mouse embryonic brain, as well as a mouse glioblastoma model, by in situ hybridization.
|
11126911 |
2000 |
Adult Glioblastoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
By use of a digoxigenin-labeled DDR1 riboprobe, we investigated the expression of DDR1 messenger ribonucleic acid in a prospective series of 30 resected human primary and metastatic brain neoplasms, nonneoplastic human brain, and mouse embryonic brain, as well as a mouse glioblastoma model, by in situ hybridization.
|
11126911 |
2000 |
Childhood Glioblastoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
By use of a digoxigenin-labeled DDR1 riboprobe, we investigated the expression of DDR1 messenger ribonucleic acid in a prospective series of 30 resected human primary and metastatic brain neoplasms, nonneoplastic human brain, and mouse embryonic brain, as well as a mouse glioblastoma model, by in situ hybridization.
|
11126911 |
2000 |
Brain Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
By use of a digoxigenin-labeled DDR1 riboprobe, we investigated the expression of DDR1 messenger ribonucleic acid in a prospective series of 30 resected human primary and metastatic brain neoplasms, nonneoplastic human brain, and mouse embryonic brain, as well as a mouse glioblastoma model, by in situ hybridization.
|
11126911 |
2000 |
Central Nervous System Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The expression of DDR1 by tumor cells of CNS neoplasms and by primitive cells of the embryonic ventricular zone suggests that DDR1 is a potentially useful marker of tumor cells within the CNS.
|
11126911 |
2000 |
androgen independent prostate cancer
|
0.010 |
Biomarker
|
disease |
BEFREE |
Methylation of the NEP promoter was present in androgen-independent PC cell lines but not in androgen-dependent or small-cell derived PC cell lines and in 3 of 21 (14%) primary PCs from patients with androgen-dependent disease.
|
10815884 |
2000 |
Heart failure
|
0.210 |
AlteredExpression
|
disease |
BEFREE |
Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies from patients with aortic valve stenosis (AS, n=19) and heart failure due to dilated cardiomyopathy (DCM, n=14), and control subjects with normal systolic function (CON, n=14).
|
11804980 |
2002 |
Congestive heart failure
|
0.210 |
AlteredExpression
|
disease |
BEFREE |
Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies from patients with aortic valve stenosis (AS, n=19) and heart failure due to dilated cardiomyopathy (DCM, n=14), and control subjects with normal systolic function (CON, n=14).
|
11804980 |
2002 |
Aortic Valve Stenosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies from patients with aortic valve stenosis (AS, n=19) and heart failure due to dilated cardiomyopathy (DCM, n=14), and control subjects with normal systolic function (CON, n=14).
|
11804980 |
2002 |
Cardiomyopathy, Dilated
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Methods and Results- NEP mRNA was quantitated by real-time polymerase chain reaction (PCR) in left ventricular biopsies from patients with aortic valve stenosis (AS, n=19) and heart failure due to dilated cardiomyopathy (DCM, n=14), and control subjects with normal systolic function (CON, n=14).
|
11804980 |
2002 |