|
Inflammatory Bowel Diseases
|
0.410 |
GeneticVariation
|
group |
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
Inflammatory Bowel Diseases
|
0.410 |
Biomarker
|
group |
CTD_human |
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
|
21983784 |
2011 |
|
Inflammatory Bowel Diseases
|
0.410 |
GeneticVariation
|
group |
BEFREE |
Joint analysis of 1851 IBD patients (1062 CD, 789 UC) and 1936 controls demonstrated strong association to the IL18RAP rs917997 SNP for both CD and UC (p(IBD) 1.9 x 10(-8); OR 1.35).
|
18439550 |
2008 |
|
Ulcerative Colitis
|
0.310 |
Biomarker
|
disease |
CTD_human |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
Ulcerative Colitis
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
Joint analysis of 1851 IBD patients (1062 CD, 789 UC) and 1936 controls demonstrated strong association to the IL18RAP rs917997 SNP for both CD and UC (p(IBD) 1.9 x 10(-8); OR 1.35).
|
18439550 |
2008 |
|
Crohn Disease
|
0.120 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
Crohn Disease
|
0.120 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Crohn Disease
|
0.120 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Crohn Disease
|
0.120 |
GeneticVariation
|
disease |
BEFREE |
Additionally, we show that T1D risk alleles residing at the PTPN22, IL27, IL18RAP and IL10 loci protect against CD.
|
20176734 |
2010 |
|
Crohn Disease
|
0.120 |
GeneticVariation
|
disease |
BEFREE |
Joint analysis of 1851 IBD patients (1062 CD, 789 UC) and 1936 controls demonstrated strong association to the IL18RAP rs917997 SNP for both CD and UC (p(IBD) 1.9 x 10(-8); OR 1.35).
|
18439550 |
2008 |
|
Asthma
|
0.110 |
GeneticVariation
|
disease |
GWASDB |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
|
Asthma
|
0.110 |
Biomarker
|
disease |
LHGDN |
Association of IL1RL1, IL18R1, and IL18RAP gene cluster polymorphisms with asthma and atopy.
|
18774397 |
2008 |
|
Lupus Erythematosus, Systemic
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Transancestral mapping and genetic load in systemic lupus erythematosus.
|
28714469 |
2017 |
|
Interleukin 1 Receptor-Like 1 Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Connecting genetic risk to disease end points through the human blood plasma proteome.
|
28240269 |
2017 |
|
Eosinophil count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Blood basophil count (lab test)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Allergic Reaction
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
|
23817569 |
2013 |
|
Triglycerides measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Celiac Disease
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis provides robust estimates that IL18RAP rs917997 and CCR3 rs6441961 are potential risk factors for celiac disease in European populations.
|
26289103 |
2015 |
|
Celiac Disease
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Recent genome-wide association studies have identified 1q31 (RGS1), 2q11-12 (IL18RAP), 3p21 (CCR1/CCR3/CCR2), 3q25-26 (IL12A/SCHIP1), 3q28 (LPP), 4q27 (IL2/IL21), 6q25 (TAGAP) and 12q24 (SH2B3) as susceptibility regions for coeliac disease (CD).
|
19693089 |
2010 |
|
Celiac Disease
|
0.060 |
Biomarker
|
disease |
BEFREE |
Association of IL18RAP and CCR3 with coeliac disease in the Spanish population.
|
19542083 |
2009 |
|
Celiac Disease
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Two putative isoforms of IL18RAP were detected and the ratios and total levels of these isoforms may contribute to the aetiology of coeliac disease.
|
19103669 |
2009 |
|
Celiac Disease
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
The effects of the IL18RAP and TAGAP alleles confer protection in type 1 diabetes and susceptibility in celiac disease.
|
19073967 |
2008 |
|
Celiac Disease
|
0.060 |
GeneticVariation
|
disease |
LHGDN |
Newly identified genetic risk variants for celiac disease related to the immune response.
|
18311140 |
2008 |
|
Diabetes Mellitus, Insulin-Dependent
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Autoantibodies to insulin (IAA), GAD (GADA), insulinoma-associated antigen-2 (IA-2A) and zinc transporter 8 (ZnT8A) were measured in follow-up sera, and genotyping for type 1 diabetes susceptibility genes (HLA-DR/HLA-DQ, INS variable number of tandem repeats [VNTR] and single nucleotide polymorphisms at PTPN22, PTPN2, ERBB3, IL2, SH2B3, CTLA4, IFIH1, KIAA0350 [also known as CLEC16A], CD25, IL18RAP, IL10, COBL) was performed on the DNA samples of children born to a parent with type 1 diabetes and prospectively followed from birth for up to 22 years.
|
23539116 |
2013 |