|
Peripheral arterial stenosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
IL1RL1 single nucleotide polymorphism predicts sST2 level and mortality in coronary and peripheral artery disease.
|
28110258 |
2017 |
|
Peripheral Arterial Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
IL1RL1 single nucleotide polymorphism predicts sST2 level and mortality in coronary and peripheral artery disease.
|
28110258 |
2017 |
|
Pancreatitis, Chronic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
IL33, ST2L and IL1RAcP were expressed by alpha-SMA-positive myofibroblasts in the fibrosis of chronic pancreatitis.
|
19996325 |
2010 |
|
Osteopenia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Using transgenic mice overexpressing human TNF, which develop spontaneous joint inflammation and cartilage destruction, we show that administration of IL-33 or an IL-33R (ST2L) agonistic Ab inhibited cartilage destruction, systemic bone loss, and osteoclast differentiation.
|
21515798 |
2011 |
|
Neutrophilic asthma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The inflammasome proteins nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 (NLRP1), NLRP3, and nucleotide-binding oligomerization domain (NOD)-like receptor C4 (NLRC4) were associated with neutrophilic asthma and with sputum IL-1β protein levels, whereas eosinophilic asthma was associated with an IL-13-induced T<sub>H</sub>2 signature and IL-1 receptor-like 1 (IL1RL1) mRNA expression.
|
28528200 |
2018 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.
|
26775708 |
2016 |
|
Neoplasms
|
0.080 |
GeneticVariation
|
group |
BEFREE |
The stemline karyotype of the tumor was 46,XY,del(2) (q33q36),der(4)t(4;?)(p16;?),der(5;15)(q10;q10),der(8)t(8;?13)(p21 ;?),-13,- 13,-15,+3mar.
|
1486562 |
1992 |
|
Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Statistical analysis demonstrated that decreased ST2 expression was significantly associated with advanced tumor node metastasis stage (P<0.001) and tumor differentiation (P<0.001).
|
31186802 |
2019 |
|
Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Vascular endothelial growth factor (VEGF) is one of the key factors in tumor neoangiogenesis, acting through its receptors KDR (VEGFR-2) and fit-1 (VEGFR-1) expressed on endothelial cells.
|
10616207 |
1999 |
|
Neoplasms
|
0.080 |
GeneticVariation
|
group |
BEFREE |
All had hyperdiploid tumor karyotypes; however, in the case with t(q25;q32), the der(4) was the only abnormality in the stemline.
|
9258666 |
1997 |
|
Neoplasms
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Cytogenetic studies revealed 45, XX, add or dup (7)(q32q36) in one neoplasm, and 83-89, XXXX, -1 ,-3, del (3)(q11.1q2?1), der(4)t(4;?22) (q32;q11.2), -14, -22 in a second tumor.
|
10403299 |
1999 |
|
Neoplasms
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Cytogenetic analysis of the relapsed tumor showed a complex karyotype: 47,XX,i(1)(q10), der(4)t(4;19) (q33 approximately q35;q13.1), + 8,t(15;17)(q24;p11.2 approximately p12),der(19)t (19;20)(q13.1;p11.2),der(22)t(20;22)(q13;q13).
|
15547779 |
2005 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
We found exogenously administered recombinant mouse interleukin 33 promoted tumor size and induced tumor-infiltrating ST2L<sup>+</sup> regulatory T cells in tumor-bearing mice while neutralizing interleukin-33 or ST2L inhibited tumor size and decreased ST2L<sup>+</sup> regulatory T cells.
|
29950152 |
2018 |
|
Neoplasm Metastasis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Statistical analysis demonstrated that decreased ST2 expression was significantly associated with advanced tumor node metastasis stage (P<0.001) and tumor differentiation (P<0.001).
|
31186802 |
2019 |
|
Nasal Polyps
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.
|
30643255 |
2019 |
|
Muscular Dystrophy, Duchenne
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Increased ST2 levels were found in serum of DMD subjects compared to healthy volunteers and further elevated in DMD subjects with cardiomyopathy.
|
28821969 |
2017 |
|
Multiple Myeloma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The t(4;14) translocation occurs frequently in multiple myeloma (MM) and results in the simultaneous dysregulated expression of 2 potential oncogenes, FGFR3 (fibroblast growth factor receptor 3) from der(14) and multiple myeloma SET domain protein/Wolf-Hirschhorn syndrome candidate gene 1 from der(4).
|
11157491 |
2001 |
|
Multiple Myeloma
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
The karyotypically silent t(4;14)(p16.3;q32) translocation can be found in approximately 15-20% of multiple myeloma (MM) patients and results in the ectopic expression of fibroblast growth factor receptor 3 (FGFR3) from der4.
|
12368157 |
2002 |
|
Multiple Myeloma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
The t(4;14) translocation occurs in 25% of multiple myeloma (MM) and results in both the ectopic expression of fibroblast growth factor receptor 3 (FGFR3) from der4 and immunoglobulin heavy chain-MMSET hybrid messenger RNA transcripts from der14.
|
10648414 |
2000 |
|
Multiple Myeloma
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
The t(4;14) translocation in multiple myeloma (MM) simultaneously dysregulates two apparent oncogenes: fibroblast growth factor receptor 3 (FGFR3) controlled by the 3' immunoglobulin heavy chain enhancer on der(14) and MMSET controlled by the intronic Emu enhancer on der(4).
|
20393505 |
2010 |
|
Malignant neoplasm of stomach
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In this study, we find that IL-33 and its receptor ST2L are upregulated in the human GC and served as prognostic markers for poor survival of GC patients.
|
31659258 |
2020 |
|
Malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.
|
26775708 |
2016 |
|
Malignant neoplasm of colon and/or rectum
|
0.020 |
Biomarker
|
disease |
BEFREE |
Therefore, we compared multiple rounds of one sample FIT (1-FIT) with 2-FIT screening with respect to participation, positive predictive value (PPV), diagnostic yield, and interval colorectal cancer.
|
31196734 |
2019 |
|
Malignant neoplasm of colon and/or rectum
|
0.020 |
Biomarker
|
disease |
BEFREE |
Role of the IL-33/ST2L axis in colorectal cancer progression.
|
29329638 |
2019 |
|
Lymphoma
|
0.010 |
GeneticVariation
|
group |
BEFREE |
A t(11;14)(q13;q32) was consistently observed in one patient with cb-cc lymphoma together with inv(1) (p22p36), der(4)t(4;?)(p16;?), del(6)(q13) and other variable changes.
|
1913607 |
1991 |