|
Major Depressive Disorder
|
0.400 |
GeneticVariation
|
disease |
GWASCAT |
GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.
|
30219690 |
2019 |
|
Major Depressive Disorder
|
0.400 |
Biomarker
|
disease |
PSYGENET |
We observed a significant positive correlation between layers II and IV of the dorso-lateral prefrontal cortex (DLPFC) in the percentage of MR-GEF expressing neurons in individuals with bipolar disorder, but not in individuals with schizophrenia, major depressive disorder or in controls.
|
20436929 |
2010 |
|
Bipolar Disorder
|
0.310 |
Biomarker
|
disease |
PSYGENET |
We observed a significant positive correlation between layers II and IV of the dorso-lateral prefrontal cortex (DLPFC) in the percentage of MR-GEF expressing neurons in individuals with bipolar disorder, but not in individuals with schizophrenia, major depressive disorder or in controls.
|
20436929 |
2010 |
|
Bipolar Disorder
|
0.310 |
Biomarker
|
disease |
BEFREE |
Expression of the Rap1 guanine nucleotide exchange factor, MR-GEF, is altered in individuals with bipolar disorder.
|
20436929 |
2010 |
|
Psychotic Disorders
|
0.310 |
Biomarker
|
group |
BEFREE |
Expression of both Dlx1/2 and MR-GEF is retained in both adult mouse and human forebrain where, in human, decreased Dlx1 expression has been associated with psychosis.
|
20436929 |
2010 |
|
Schizophrenia
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
We therefore compared MR-GEF expression by in situ hybridization in individuals with major psychiatric disorders (schizophrenia, bipolar disorder, major depression) and control individuals.
|
20436929 |
2010 |
|
Nonorganic psychosis
|
0.310 |
Biomarker
|
disease |
BEFREE |
Expression of both Dlx1/2 and MR-GEF is retained in both adult mouse and human forebrain where, in human, decreased Dlx1 expression has been associated with psychosis.
|
20436929 |
2010 |
|
Unipolar Depression
|
0.300 |
Biomarker
|
disease |
PSYGENET |
We observed a significant positive correlation between layers II and IV of the dorso-lateral prefrontal cortex (DLPFC) in the percentage of MR-GEF expressing neurons in individuals with bipolar disorder, but not in individuals with schizophrenia, major depressive disorder or in controls.
|
20436929 |
2010 |
|
Amphetamine-Related Disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
Genome-wide association for methamphetamine dependence: convergent results from 2 samples.
|
18316681 |
2008 |
|
Amphetamine Addiction
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association for methamphetamine dependence: convergent results from 2 samples.
|
18316681 |
2008 |
|
Amphetamine Abuse
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association for methamphetamine dependence: convergent results from 2 samples.
|
18316681 |
2008 |
|
Diabetes Mellitus
|
0.100 |
Biomarker
|
group |
BEFREE |
The slower drop in kidney function was associated with lower SBP (P=.04), higher GFR (P=.01), lower albuminuria (P=.01), not diabetes mellitus (P=.01) and treatment with spironolactone (P=.02).
|
31451203 |
2020 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
Biomarker
|
disease |
BEFREE |
To evaluate the association between sarcopenic obesity and the decline in estimated GFR in people with type 2 diabetes.
|
31621107 |
2020 |
|
Hypertensive disease
|
0.100 |
Biomarker
|
group |
BEFREE |
In addition, Lee index, left ventricular end-systolic, end-diastolic and left atrial diameter were significantly higher, GFR values were significantly lower in the group with cardiac events.Multivariate regression analysis showed that smoking (OR 5.031, 95% CI 1.602 to 15.794), presence of hypertension (OR 5.133, 95% CI 1.297 to 20.308) and aortic arch calcification (OR 6.920, 95% CI 3.890 to 12.310) are independent predictors of major cardiac events within 30-day of elective orthopedic surgery.
|
30595343 |
2020 |
|
Kidney Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Although decreased eGFR in type 2 diabetes patients was not prevalent, the strategies to prevent the progressive decline of GFR should be done to prevent patients from progressing to advanced renal disease.
|
31494076 |
2020 |
|
Kidney Failure, Acute
|
0.100 |
Biomarker
|
disease |
BEFREE |
In experimental models of AKI, infusion of NP prevented post-ischemic fall in renal blood flow (RBF) or improvement in RBF, GFR, diuresis and natriuresis and demonstrated anti-inflammatory properties.
|
31812538 |
2020 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The associations of soluble DPP-4 levels with serum creatinine and GFR remained significant after adjusting for age, body mass index, and duration of diabetes.
|
30302966 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
To address this issue, we analyzed GFR follow-up data on participants with type 1 diabetes undergoing <sup>125</sup>I-iothalamate clearance on entry into the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications study.
|
31123181 |
2019 |
|
Diabetes Mellitus
|
0.100 |
Biomarker
|
group |
BEFREE |
The associations of soluble DPP-4 levels with serum creatinine and GFR remained significant after adjusting for age, body mass index, and duration of diabetes.
|
30302966 |
2019 |
|
Diabetes Mellitus
|
0.100 |
Biomarker
|
group |
BEFREE |
Cross-sectional study in 134 CKD patients in stages 3-5 (mean e-GFR: 19.4±8.7ml/min/1.73m<sup>2</sup>; males 68.7% and primary CKD etiology was diabetes mellitus, 35.8%).
|
30293714 |
2019 |
|
Diabetes Mellitus
|
0.100 |
Biomarker
|
group |
BEFREE |
To address this issue, we analyzed GFR follow-up data on participants with type 1 diabetes undergoing <sup>125</sup>I-iothalamate clearance on entry into the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications study.
|
31123181 |
2019 |
|
Diabetes Mellitus
|
0.100 |
Biomarker
|
group |
BEFREE |
We evaluated the performance of cystatin C-based equations alone or in combination with creatinine to estimate GFR in DM patients.
|
30723243 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
Biomarker
|
disease |
BEFREE |
In American Indians with type 2 diabetes and preserved GFR at baseline, increasing ACR reflects the progression of earlier structural glomerular lesions, whereas early GFR decline may not accurately reflect such lesions.
|
31152118 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to provide evidence for the hypothesis that estimated glomerular filtration rate from serum Cystatin C (eGFRcys) is better to be determined for all elderly type 2 diabetes mellitus (T2DM) patients based on eGFRcys upward and downward reclassification rate for hypothetical metformin dose reduction by eGFRcys at the GFR decision point of 45 mL/min/1.73 m<sup>2</sup> .
|
30218617 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Error of Estimated GFR in Type 2 Diabetes Mellitus.
|
31561432 |
2019 |