|
HEARING LOSS, CISPLATIN-INDUCED, SUSCEPTIBILITY TO
|
0.300 |
Biomarker
|
disease |
CTD_human |
Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss.
|
25665007 |
2015 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits.
|
28604731 |
2017 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Exome-wide association study of plasma lipids in >300,000 individuals.
|
29083408 |
2017 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.
|
27494321 |
2016 |
|
Sudden Cardiac Death
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
|
21658281 |
2011 |
|
Sudden Cardiac Arrest
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
|
21658281 |
2011 |
|
Chronic osteomyelitis
|
0.100 |
GeneticVariation
|
disease |
CLINVAR |
|
|
|
|
Malignant Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Meta-analysis shown that ACYP2 rs1682111 was associated with the risk of cancer (OR = 0.90, 95% CI: 0.78-1.05, p = 0.02).
|
31124313 |
2019 |
|
Colorectal Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
It has been reported that ACYP2 gene was associated with the development of gastric cancer and colorectal cancer, but it is not clear that the relationship between ACYP2 gene and GI cancer in Chinese Han population.
|
31070019 |
2019 |
|
Primary malignant neoplasm
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Meta-analysis shown that ACYP2 rs1682111 was associated with the risk of cancer (OR = 0.90, 95% CI: 0.78-1.05, p = 0.02).
|
31124313 |
2019 |
|
Malignant neoplasm of colon and/or rectum
|
0.020 |
Biomarker
|
disease |
BEFREE |
It has been reported that ACYP2 gene was associated with the development of gastric cancer and colorectal cancer, but it is not clear that the relationship between ACYP2 gene and GI cancer in Chinese Han population.
|
31070019 |
2019 |
|
Malignant neoplasm of breast
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Single Nucleotide Polymorphisms in the Acylphosphatase 2 Gene and The SNP-SNP Interactions on the Risk of Breast Cancer in Chinese Han Women.
|
29033240 |
2018 |
|
Breast Carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Single Nucleotide Polymorphisms in the Acylphosphatase 2 Gene and The SNP-SNP Interactions on the Risk of Breast Cancer in Chinese Han Women.
|
29033240 |
2018 |
|
Malignant Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
We investigated the association between single nucleotide polymorphisms (SNPs) in ACYP2, which has been associated with telomere length in several types of cancer, and the risk of CRC in a Chinese Han population.
|
28039478 |
2017 |
|
Colorectal Carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Genetic polymorphisms in the telomere length-related gene ACYP2 are associated with the risk of colorectal cancer in a Chinese Han population.
|
28039478 |
2017 |
|
High altitude pulmonary edema
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The CC genotype of rs17045754 had a protect effect on HAPE patients, and it was found to have a 0.29-fold reduced risk of HAPE in the recessive model.Although additional, larger population-based studies are needed to confirm these findings, our study shed light on the association between ACYP2 variant and HAPE risk in Han Chinese population for the first time.
|
28353602 |
2017 |
|
Primary malignant neoplasm
|
0.020 |
GeneticVariation
|
group |
BEFREE |
We investigated the association between single nucleotide polymorphisms (SNPs) in ACYP2, which has been associated with telomere length in several types of cancer, and the risk of CRC in a Chinese Han population.
|
28039478 |
2017 |
|
Malignant neoplasm of colon and/or rectum
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Genetic polymorphisms in the telomere length-related gene ACYP2 are associated with the risk of colorectal cancer in a Chinese Han population.
|
28039478 |
2017 |
|
Brain Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
The variant rs1872328 in the ACYP2 gene was recently identified as a risk factor for the development of cisplatin-induced ototoxicity in children with brain tumors.
|
26928270 |
2016 |
|
Malignant neoplasm of breast
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
In sum, our findings reveal significant associations between SNPs in the ACYP2 gene and BC risk in a Han Chinese population.
|
27894080 |
2016 |
|
High altitude pulmonary edema
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to determine whethher there is any association between ACYP2 polymorphism and the risk of HAPE.
|
27552709 |
2016 |
|
Breast Carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
In sum, our findings reveal significant associations between SNPs in the ACYP2 gene and BC risk in a Han Chinese population.
|
27894080 |
2016 |
|
Brain Neoplasms
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Taking a genome-wide association study approach, we identified inherited genetic variations in ACYP2 associated with cisplatin-related ototoxicity (rs1872328: P = 3.9 × 10(-8), hazard ratio = 4.5) in 238 children with newly diagnosed brain tumors, with independent replication in 68 similarly treated children.
|
25665007 |
2015 |