NQO1, NAD(P)H quinone dehydrogenase 1, 1728

N. diseases: 368; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1131341
rs1131341 		0.925 0.160 16 69714966 missense variant G/A;C snv 3.2E-02 2.6E-02
CUI: C0685938
Disease: Malignant neoplasm of gastrointestinal tract
Malignant neoplasm of gastrointestinal tract 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2014 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0007097
Disease: Carcinoma
Carcinoma 		Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0278498
Disease: Malignant neoplasm of stomach stage IV
Malignant neoplasm of stomach stage IV 		0.010 1.000 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0685938
Disease: Malignant neoplasm of gastrointestinal tract
Malignant neoplasm of gastrointestinal tract 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2014 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		Eye Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2012 2012
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.020 0.500 2 2012 2019
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0007097
Disease: Carcinoma
Carcinoma 		Neoplasms 0.020 1.000 2 2012 2014
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2012 2012
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.020 0.500 2 2012 2019
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		Neoplasms; Male Urogenital Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs1258159645
rs1258159645 		0.630 0.600 16 69711128 missense variant G/A snv 7.0E-06
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		Neoplasms; Male Urogenital Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs1319831679
rs1319831679 		1.000 0.080 16 69711169 missense variant C/T snv 4.0E-06 7.0E-06
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0023418
Disease: leukemia
leukemia 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs372951639
rs372951639 		1.000 0.040 16 69718484 missense variant A/T snv 1.6E-05 3.5E-05
CUI: C0017638
Disease: Glioma
Glioma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs8053497
rs8053497 		16 69721997 intron variant A/G snv 3.7E-02
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.700 1.000 1 2012 2012
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.060 1.000 6 2011 2017
dbSNP: rs1800566
rs1800566 		0.576 0.680 16 69711242 missense variant G/A snv 0.25 0.21
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.060 1.000 6 2011 2017