GREM1, gremlin 1, DAN family BMP antagonist, 26585

N. diseases: 179; N. variants: 8
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs10318
rs10318 		0.882 0.080 15 32733778 3 prime UTR variant C/T snv 0.16
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.730 1.000 4 2008 2015
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C2677123
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.800 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		Digestive System Diseases; Neoplasms 0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C2675481
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C1837315
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C1319315
Disease: Adenocarcinoma of large intestine
Adenocarcinoma of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C0346629
Disease: Malignant neoplasm of large intestine
Malignant neoplasm of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 3 2014 2019
dbSNP: rs73376930
rs73376930 		0.790 0.080 15 32720301 intron variant A/G snv 0.25
CUI: C3554460
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		0.700 1.000 3 2014 2019
dbSNP: rs10318
rs10318 		0.882 0.080 15 32733778 3 prime UTR variant C/T snv 0.16
CUI: C1302401
Disease: Adenoma of large intestine
Adenoma of large intestine 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs10318
rs10318 		0.882 0.080 15 32733778 3 prime UTR variant C/T snv 0.16
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2015 2015
dbSNP: rs1129456
rs1129456 		1.000 0.120 15 32734466 3 prime UTR variant A/T snv 0.19
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases 0.010 1.000 1 2010 2010
dbSNP: rs3743104
rs3743104 		1.000 0.120 15 32731784 3 prime UTR variant A/G;T snv
CUI: C0848558
Disease: Hypospadias
Hypospadias 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases 0.700 1.000 1 2014 2014
dbSNP: rs1332974507
rs1332974507 		0.925 0.120 15 32731180 missense variant C/T snv 4.0E-06 7.0E-06
CUI: C1398522
Disease: Cleft palate and bilateral cleft lip
Cleft palate and bilateral cleft lip 		0.010 1.000 1 2018 2018
dbSNP: rs1332974507
rs1332974507 		0.925 0.120 15 32731180 missense variant C/T snv 4.0E-06 7.0E-06
CUI: C0008925
Disease: Cleft Palate
Cleft Palate 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases 0.010 1.000 1 2018 2018
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C1319315
Disease: Adenocarcinoma of large intestine
Adenocarcinoma of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C2677123
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C3554460
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C1837315
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C2675481
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2015 2015
dbSNP: rs2293582
rs2293582 		0.790 0.080 15 32718211 non coding transcript exon variant G/A snv 0.23 0.20
CUI: C0346629
Disease: Malignant neoplasm of large intestine
Malignant neoplasm of large intestine 		Digestive System Diseases; Neoplasms 0.700 1.000 1 2015 2015