HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.020 1.000 2 2008 2012
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		Musculoskeletal Diseases; Nervous System Diseases 0.010 < 0.001 1 2012 2012
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases 0.010 1.000 1 2006 2006
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2005 2005
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2006 2006
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 1.000 1 2013 2013
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2013 2013
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0424101
Disease: Inattention
Inattention 		0.010 1.000 1 2006 2006
dbSNP: rs75634836
rs75634836 		0.807 0.160 13 46835532 missense variant C/A;T snv 4.0E-06
CUI: C0564567
Disease: Impulsive character (finding)
Impulsive character (finding) 		0.010 1.000 1 2010 2010
dbSNP: rs2770292
rs2770292 		1.000 0.040 13 46860971 intron variant C/G snv 0.18
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.010 1.000 1 2007 2007
dbSNP: rs3125
rs3125 		0.925 0.080 13 46834716 3 prime UTR variant C/G;T snv
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs3125
rs3125 		0.925 0.080 13 46834716 3 prime UTR variant C/G;T snv
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs3125
rs3125 		0.925 0.080 13 46834716 3 prime UTR variant C/G;T snv
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.010 1.000 1 2019 2019
dbSNP: rs3125
rs3125 		0.925 0.080 13 46834716 3 prime UTR variant C/G;T snv
CUI: C0154575
Disease: Rumination Disorders
Rumination Disorders 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.100 0.800 10 2010 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder 		Mental Disorders 0.060 0.833 6 2007 2018
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		Mental Disorders 0.050 1.000 5 2010 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.030 0.667 3 2014 2019
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.030 1.000 3 2017 2017
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.020 1.000 2 2006 2018
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2011 2017
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		Mental Disorders 0.020 1.000 2 2014 2014
dbSNP: rs6311
rs6311 		0.645 0.640 13 46897343 upstream gene variant C/T snv 0.40
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2009 2014