LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C4016417
Disease: VASCULAR DEMENTIA, SUSCEPTIBILITY TO
VASCULAR DEMENTIA, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C1856170
Disease: ALZHEIMER DISEASE, SUSCEPTIBILITY TO
ALZHEIMER DISEASE, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs2239704
rs2239704 		0.732 0.320 6 31572364 5 prime UTR variant A/C snv 0.64
CUI: C2750103
Disease: LEPROSY, EARLY-ONSET, SUSCEPTIBILITY TO
LEPROSY, EARLY-ONSET, SUSCEPTIBILITY TO 		0.700 0
dbSNP: rs909253
rs909253 		0.641 0.600 6 31572536 intron variant A/G;T snv
CUI: C1835223
Disease: PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO (finding)
PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO (finding) 		0.700 0
dbSNP: rs909253
rs909253 		0.641 0.600 6 31572536 intron variant A/G;T snv
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.700 0
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2012 2012
dbSNP: rs2229094
rs2229094 		0.776 0.320 6 31572779 missense variant T/C snv 0.27 0.27
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		Musculoskeletal Diseases 0.010 < 0.001 1 2017 2017
dbSNP: rs2239704
rs2239704 		0.732 0.320 6 31572364 5 prime UTR variant A/C snv 0.64
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		Musculoskeletal Diseases 0.010 < 0.001 1 2017 2017
dbSNP: rs28445017
rs28445017 		6 31559979 downstream gene variant G/A;C snv
CUI: C0442874
Disease: Neuropathy
Neuropathy 		Nervous System Diseases 0.010 < 0.001 1 2016 2016
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.020 0.500 2 2014 2014
dbSNP: rs909253
rs909253 		0.641 0.600 6 31572536 intron variant A/G;T snv
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases 0.020 0.500 2 2006 2019
dbSNP: rs909253
rs909253 		0.641 0.600 6 31572536 intron variant A/G;T snv
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.020 0.500 2 2006 2013
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.030 0.667 3 2005 2010
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.720 0.667 3 2011 2019
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.020 1.000 2 2010 2017
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases 0.720 1.000 2 2005 2007
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0031099
Disease: Periodontitis
Periodontitis 		Stomatognathic Diseases 0.020 1.000 2 2014 2019
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2015 2017
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2015 2017
dbSNP: rs1799964
rs1799964 		0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		Infections 0.020 1.000 2 2013 2019
dbSNP: rs1799964
rs1799964 		0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19
CUI: C0011311
Disease: Dengue Fever
Dengue Fever 		Infections 0.020 1.000 2 2013 2015
dbSNP: rs1799964
rs1799964 		0.608 0.760 6 31574531 upstream gene variant T/C snv 0.19
CUI: C0032460
Disease: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases 0.020 1.000 2 2013 2014
dbSNP: rs1800630
rs1800630 		0.701 0.480 6 31574699 upstream gene variant C/A snv 0.14
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.020 1.000 2 2010 2015
dbSNP: rs2239704
rs2239704 		0.732 0.320 6 31572364 5 prime UTR variant A/C snv 0.64
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.710 1.000 2 2014 2017
dbSNP: rs2844484
rs2844484 		0.807 0.320 6 31568447 upstream gene variant A/G snv 0.64
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.700 1.000 2 2007 2009