LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		Cardiovascular Diseases 0.010 1.000 1 2006 2006
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2009 2009
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 < 0.001 1 2012 2012
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		Digestive System Diseases 0.010 1.000 1 2006 2006
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		Cardiovascular Diseases 0.010 1.000 1 2005 2005
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		Infections; Respiratory Tract Diseases 0.010 1.000 1 2012 2012
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2009 2009
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		Cardiovascular Diseases 0.010 1.000 1 2006 2006
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0006277
Disease: Bronchitis
Bronchitis 		Infections; Respiratory Tract Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		Nutritional and Metabolic Diseases 0.010 1.000 1 2005 2005
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 2014 2014
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C1847835
Disease: VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) 		Skin and Connective Tissue Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C0042900
Disease: Vitiligo
Vitiligo 		Skin and Connective Tissue Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2009 2009
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.010 1.000 1 2014 2014
dbSNP: rs1041981
rs1041981 		0.667 0.520 6 31573007 missense variant C/A snv 0.35 0.38
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		Cardiovascular Diseases 0.010 1.000 1 2011 2011
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1330189219
rs1330189219 		0.882 0.080 6 31573570 synonymous variant C/T snv 4.0E-06
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2008 2008
dbSNP: rs1799724
rs1799724 		0.600 0.680 6 31574705 upstream gene variant C/T snv 8.5E-02
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2015 2015