|
rs12583006
|
TNFSF13B
|
Liver diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
This study examined BAFF rs9514828 and rs12583006 polymorphisms in 386 patients with various liver diseases related to chronic HBV infection, 69 HBV infection resolvers, and 191 healthy controls.
|
28627389 |
2017 |
|
rs9514828
|
TNFSF13B
|
Hepatitis
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels.
|
28627389 |
2017 |
|
rs9514828
|
TNFSF13B
|
Cirrhosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The results showed that patients with chronic hepatitis had higher frequencies of rs9514828 genotype TT (19.75% vs. 11.86%, OR=2.397, 95% CI=1.121-5.125, P=0.023), genotypes CT+TT (74.69% vs. 63.55%, OR=1.478, 95% CI=1.050-2.080, P=0.045), and allele T (47.22% vs. 37.72%, OR=1.478, 95% CI=1.050-2.080, P=0.025) compared with patients with cirrhosis.
|
28627389 |
2017 |
|
rs9514828
|
TNFSF13B
|
Liver diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
This study examined BAFF rs9514828 and rs12583006 polymorphisms in 386 patients with various liver diseases related to chronic HBV infection, 69 HBV infection resolvers, and 191 healthy controls.
|
28627389 |
2017 |
|
rs9514828
|
TNFSF13B
|
Liver Cirrhosis
|
|
0.010 |
GeneticVariation |
BEFREE |
The results showed that patients with chronic hepatitis had higher frequencies of rs9514828 genotype TT (19.75% vs. 11.86%, OR=2.397, 95% CI=1.121-5.125, P=0.023), genotypes CT+TT (74.69% vs. 63.55%, OR=1.478, 95% CI=1.050-2.080, P=0.045), and allele T (47.22% vs. 37.72%, OR=1.478, 95% CI=1.050-2.080, P=0.025) compared with patients with cirrhosis.
|
28627389 |
2017 |
|
rs1041569
|
TNFSF13B
|
Chronic Lymphocytic Leukemia
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results point to a possible association between the rs9514828 (CT vs. CC + TT; OR = 0.74; CI 95 % = 0.57; 0.97; p = 0.022) and rs1041569 (AT vs. AA + TT; OR = 0.72; CI 95 % = 0.54; 0.95; p = 0.021) of BAFF gene and rs61756766 (CC vs. CT; OR = 2.03; CI 95 % = 1.03; 3.99; p = 0.03) of BAFF-R gene and CLL risk.
|
27468724 |
2016 |
|
rs2893321
|
TNFSF13B
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations of rs2893321 with susceptibility to GD and AITDs and the correlation between rs2893321 and TAb exhibit a dimorphic pattern.
|
27136204 |
2016 |
|
rs9514828
|
TNFSF13B
|
B-CELL MALIGNANCY, LOW-GRADE
|
|
0.010 |
GeneticVariation |
BEFREE |
Although the obtained P-values for all 20 SNPs did not reach statistical significance for this study (α = 0.003), the high value of the global chi-squared statistic (χ(2) df = 38 = 52.65; P = 0.0586), and obtained values of odds ratio indicate that rs9514828 (BAFF), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of B-CLL.
|
26268376 |
2015 |
|
rs12583006
|
TNFSF13B
|
Primary Sjögren's syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
The low risk pSS group exhibited higher frequency of the minor A allele and AA genotype of the rs12583006 variant compared to HC.
|
23845207 |
2014 |
|
rs9514828
|
TNFSF13B
|
Primary Sjögren's syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
The high risk pSS group was characterized by higher frequency of the minor T allele of the rs9514828 BAFF polymorphism compared to HC.
|
23845207 |
2014 |
|
rs9514828
|
TNFSF13B
|
BAFF polymorphism
|
|
0.010 |
GeneticVariation |
BEFREE |
The high risk pSS group was characterized by higher frequency of the minor T allele of the rs9514828 BAFF polymorphism compared to HC.
|
23845207 |
2014 |
|
rs12428930
|
TNFSF13B
|
Chronic graft-versus-host disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD.
|
21628416 |
2011 |
|
rs16972217
|
TNFSF13B
|
Chronic graft-versus-host disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD.
|
21628416 |
2011 |
|
rs2893321
|
TNFSF13B
|
Chronic graft-versus-host disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD.
|
21628416 |
2011 |
|
rs7993590
|
TNFSF13B
|
Chronic graft-versus-host disease
|
|
0.010 |
GeneticVariation |
BEFREE |
In multivariate analyses, 4 recipient BAFF SNPs (rs16972217 [odds ratio = 2.72, P = .004], rs7993590 [odds ratio = 2.35, P = .011], rs12428930 [odds ratio2.53, P = .008], and rs2893321 [odds ratio = 2.48, P = .009]) were independent predictors of GVHD subtypes, adjusted for conventional predictors of cGVHD.
|
21628416 |
2011 |
|
rs2582869
|
TNFSF13B
|
Lymphoma, Non-Hodgkin
|
|
0.010 |
GeneticVariation |
BEFREE |
Accordingly, the single most significant SNPs associated with NHL were FAS rs4934436 (p-trend = 0.0024), IRF4 rs12211228 (p-trend = 0.0026), TNFSF13B rs2582869 (p-trend = 0.0055), TANK rs1921310 (p-trend = 0.0025), TNFSF7 rs16994592 (p-trend = 0.0024), and TNFRSF13C rs6002551 (p-trend = 0.0074).
|
19390683 |
2009 |