|
rs200748895
|
TNFSF13B
|
White Blood Cell Count procedure
|
T |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs200748895
|
TNFSF13B
|
Platelet Count measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs374039502
|
TNFSF13B
|
Platelet Component Distribution Width Measurement
|
A |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs17499386
|
TNFSF13B
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
|
22286219 |
2012 |
|
rs9514828
|
TNFSF13B
|
Hepatitis B
|
|
0.020 |
GeneticVariation |
BEFREE |
Regarding BAFF polymorphisms, the frequency of rs9514828 CT + TT genotypes was higher distributed in patients with chronic HBV infection compared with healthy controls (58.0% vs. 46.0%, P = 0.029).
|
30660167 |
2019 |
|
rs9514828
|
TNFSF13B
|
Hepatitis B
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels.
|
28627389 |
2017 |
|
rs9514828
|
TNFSF13B
|
Chronic Lymphocytic Leukemia
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results point to a possible association between the rs9514828 (CT vs. CC + TT; OR = 0.74; CI 95 % = 0.57; 0.97; p = 0.022) and rs1041569 (AT vs. AA + TT; OR = 0.72; CI 95 % = 0.54; 0.95; p = 0.021) of BAFF gene and rs61756766 (CC vs. CT; OR = 2.03; CI 95 % = 1.03; 3.99; p = 0.03) of BAFF-R gene and CLL risk.
|
27468724 |
2016 |
|
rs9514828
|
TNFSF13B
|
Chronic Lymphocytic Leukemia
|
|
0.020 |
GeneticVariation |
BEFREE |
Although the obtained P-values for all 20 SNPs did not reach statistical significance for this study (α = 0.003), the high value of the global chi-squared statistic (χ(2) df = 38 = 52.65; P = 0.0586), and obtained values of odds ratio indicate that rs9514828 (BAFF), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of B-CLL.
|
26268376 |
2015 |
|
rs9514828
|
TNFSF13B
|
T-Cell Lymphoma
|
|
0.020 |
GeneticVariation |
BEFREE |
In multivariate Cox-regression analysis, rs3742330 proved to be an independent predictor for OS, together with the commonly used International Prognostic Index (IPI) and BAFF rs9514828, another SNP we have previously reported to be associated with TCL survival, with hazard ratios (HRs) for patient death rate of 8.956 (95% CI, 1.210 to 66.318; p = 0.032) for the GA genotype and 10.145 (95% CI, 1.371 to 75.084; p = 0.023) for the AA genotype.
|
23251602 |
2012 |
|
rs9514828
|
TNFSF13B
|
T-Cell Lymphoma
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that BAFF rs9514828 polymorphism was significantly associated with TCL survival.
|
22338013 |
2012 |
|
rs2893321
|
TNFSF13B
|
Myasthenia Gravis
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic variations of rs2893321 in BAFF might be associated with susceptibility to MG in the Chinese Han population.
|
31666013 |
2019 |
|
rs4000607
|
TNFSF13B
|
BAFF polymorphism
|
|
0.010 |
GeneticVariation |
BEFREE |
We have demonstrated, for the first time, a significant association of the BAFF polymorphism rs4000607 with Graves' disease in a UK cohort.
|
30281845 |
2019 |
|
rs4000607
|
TNFSF13B
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
We have demonstrated, for the first time, a significant association of the BAFF polymorphism rs4000607 with Graves' disease in a UK cohort.
|
30281845 |
2019 |
|
rs9514828
|
TNFSF13B
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
High BAFF expression associated with active disease in systemic lupus erythematosus and relationship with rs9514828C>T polymorphism in TNFSF13B gene.
|
30747361 |
2019 |
|
rs9514828
|
TNFSF13B
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed a case-control association study to investigate two BAFF polymorphisms (rs9514828 and rs4000607) in a UK cohort of 444 patients with Graves' disease.
|
30281845 |
2019 |
|
rs12583006
|
TNFSF13B
|
Lupus Erythematosus, Discoid
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the presence of the AA genotype of the rs12583006 BAFF gene variant increased susceptibility for both lupus and lupus related plaque formation (ORs [95%CI]: 2.8 [1.1-7.1], and 4.4 [1.3-15.4] in the codominant model, respectively).
|
29859654 |
2018 |
|
rs12583006
|
TNFSF13B
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the presence of the AA genotype of the rs12583006 BAFF gene variant increased susceptibility for both lupus and lupus related plaque formation (ORs [95%CI]: 2.8 [1.1-7.1], and 4.4 [1.3-15.4] in the codominant model, respectively).
|
29859654 |
2018 |
|
rs12583006
|
TNFSF13B
|
Lupus Erythematosus
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the presence of the AA genotype of the rs12583006 BAFF gene variant increased susceptibility for both lupus and lupus related plaque formation (ORs [95%CI]: 2.8 [1.1-7.1], and 4.4 [1.3-15.4] in the codominant model, respectively).
|
29859654 |
2018 |
|
rs12583006
|
TNFSF13B
|
Lupus Vulgaris
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the presence of the AA genotype of the rs12583006 BAFF gene variant increased susceptibility for both lupus and lupus related plaque formation (ORs [95%CI]: 2.8 [1.1-7.1], and 4.4 [1.3-15.4] in the codominant model, respectively).
|
29859654 |
2018 |
|
rs374039502
|
TNFSF13B
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation |
BEFREE |
Similarly, combined analysis of the different sets evidenced a lack of association of the rs374039502 variant with GCA (P = 0.421; OR (95% CI) = 0.92 (0.75-1.13)) and SSc (P = 0.500; OR (95% CI) = 1.05 (0.91-1.22)).
|
30586461 |
2018 |
|
rs374039502
|
TNFSF13B
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphism (SNP) rs374039502, which colocalizes with the genetic variant previously implicated in autoimmunity, was genotyped using a custom TaqMan assay.
|
30586461 |
2018 |
|
rs374039502
|
TNFSF13B
|
Giant Cell Arteritis
|
|
0.010 |
GeneticVariation |
BEFREE |
Similarly, combined analysis of the different sets evidenced a lack of association of the rs374039502 variant with GCA (P = 0.421; OR (95% CI) = 0.92 (0.75-1.13)) and SSc (P = 0.500; OR (95% CI) = 1.05 (0.91-1.22)).
|
30586461 |
2018 |
|
rs1161169998
|
TNFSF13B
|
Immune thrombocytopenic purpura
|
|
0.010 |
GeneticVariation |
BEFREE |
Conclusion p.G76S mutation on the TNFRSF13B gene is responsible for ITP, and is a genetic predisposing factor for familial or sporadic ITP.
|
28834165 |
2017 |
|
rs12583006
|
TNFSF13B
|
Hepatitis B
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels.
|
28627389 |
2017 |
|
rs12583006
|
TNFSF13B
|
Hepatitis
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that the rs9514828 allele T may predispose to the liver inflammation in chronic HBV infection, and the rs9514828 and rs12583006 polymorphisms may combinatorially confer susceptibility to chronic HBV infection and resolution of the infection, possibly not through direct effect on serum BAFF levels.
|
28627389 |
2017 |