rs17590046
|
PPARGC1A
|
Essential Tremor
|
|
0.730 |
GeneticVariation |
BEFREE |
Recently, five novel single nucleotide polymorphisms (SNPs), rs10937625 in <i>STK32B</i> (serine/threonine kinase 32B), rs17590046 in <i>PPARGC1A</i> (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), and rs12764057, rs10822974, and rs7903491 in <i>CTNNA3</i> (catenin alpha 3), were found to be associated with increased risk of essential tremor (ET) in a genome-wide association study (GWAS)in individuals of Caucasian ancestry.
|
29899728 |
2018 |
rs17590046
|
PPARGC1A
|
Essential Tremor
|
|
0.730 |
GeneticVariation |
BEFREE |
And no associations were detected between rs17590046 (genotype p = 0.794; allele p = 0.791), rs12764057 (genotype p = 0.337; allele p = 0.337), rs10822974 (genotype p = 0.102; allele p = 0.100) and ET in Chinese population individually.
|
28801652 |
2017 |
rs17590046
|
PPARGC1A
|
Essential Tremor
|
|
0.730 |
GeneticVariation |
BEFREE |
After Bonferroni correction two markers, one (rs10937625) located in the serine/threonine kinase STK32B and one (rs17590046) in the transcriptional coactivator PPARGC1A were associated with essential tremor.
|
27797806 |
2016 |
rs17590046
|
PPARGC1A
|
Essential Tremor
|
T |
0.730 |
GeneticVariation |
GWASCAT |
Genome-wide association study in essential tremor identifies three new loci.
|
27797806 |
2016 |
rs2970870
|
PPARGC1A
|
Red Blood Cell Count measurement
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
rs73243607
|
PPARGC1A;LOC105374528
|
Glomerular Filtration Rate
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
|
31015462 |
2019 |
rs7667050
|
PPARGC1A
|
Glomerular Filtration Rate
|
T |
0.700 |
GeneticVariation |
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
rs34751092
|
PPARGC1A
|
Regular astigmatism - corneal
|
A |
0.700 |
GeneticVariation |
GWASCAT |
A genome-wide association study of corneal astigmatism: The CREAM Consortium.
|
29422769 |
2018 |
rs687706
|
PPARGC1A
|
Adolescent idiopathic scoliosis
|
|
0.700 |
GeneticVariation |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
rs687706
|
PPARGC1A
|
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
|
|
0.700 |
GeneticVariation |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
rs10020457
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs10517030
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs10517031
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs10517032
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs16874420
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs2324237
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs2324241
|
PPARGC1A
|
Leukemia, Myelocytic, Acute
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
|
27903959 |
2017 |
rs12501032
|
PPARGC1A
|
RESTING HEART RATE
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality.
|
27798624 |
2016 |
rs11730701
|
PPARGC1A
|
Schizophrenia
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
rs188794202
|
PPARGC1A
|
Impaired cognition
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.
|
26252872 |
2015 |
rs41359445
|
PPARGC1A
|
Impaired cognition
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.
|
26252872 |
2015 |
rs12650199
|
PPARGC1A
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide assessment of variability in human serum metabolism.
|
23281178 |
2013 |
rs16874921
|
PPARGC1A
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide assessment of variability in human serum metabolism.
|
23281178 |
2013 |
rs2970855
|
PPARGC1A
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide assessment of variability in human serum metabolism.
|
23281178 |
2013 |
rs4619879
|
PPARGC1A
|
Serum albumin measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide assessment of variability in human serum metabolism.
|
23281178 |
2013 |