FOXN3, forkhead box N3, 1112

N. diseases: 40; N. variants: 13
Disease: Hyperglycemia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8004664
rs8004664
Entrez Id: 1112
Gene Symbol: FOXN3
FOXN3
CUI: C0020456
Disease:
Hyperglycemia 		0.010 GeneticVariation BEFREE Recently, we reported that primary hepatocytes from rs8004664 hyperglycemia risk allele carriers have increased FOXN3 transcript and protein levels and liver-limited overexpression of human FOXN3, a transcriptional repressor that had not been implicated in metabolic regulation previously, increases fasting blood glucose in zebrafish. 29996093 2018