|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
In this study, we tested whether the polymorphisms of three sites (rs1876828, rs242939 and rs242941) in corticotropin-releasing hormone receptor1 (CRHR1) gene are related to 6 weeks fluoxetine antidepressant effect in 127 Han Chinese patients with MDD.
|
17258395 |
2007 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
The results show that the rs242941 G/G genotype and homozygous GAG haplotype of the three single-nucleotide polymorphisms (SNPs) are associated with fluoxetine therapeutic response in MDD patients of high-anxiety (HA).
|
17258395 |
2007 |
|
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we tested whether the polymorphisms of three sites (rs1876828, rs242939 and rs242941) in corticotropin-releasing hormone receptor1 (CRHR1) gene are related to 6 weeks fluoxetine antidepressant effect in 127 Han Chinese patients with MDD.
|
17258395 |
2007 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive episode, unspecified
|
|
0.010 |
GeneticVariation |
BEFREE |
rs110402, in CRHR1 gene, was associated with an increased risk to present a seasonal pattern and an early age of onset of the first depressive episode.
|
17467808 |
2007 |
|
rs1876831
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
heavy drinking
|
|
0.010 |
GeneticVariation |
BEFREE |
Adolescents homozygous for the C allele of rs1876831 drank higher maximum amounts of alcohol per occasion and had greater lifetime rates of heavy drinking in relation to negative life events than individuals carrying the T allele.
|
17597588 |
2008 |
|
rs778136105
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
Early studies suggest that bronchodilator reversibility and asthma worsening in patients on continuous short-acting and long-acting beta-agonists are related to the Gly16Arg genotype for the ADRB2.
|
19077707 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor T-allele of exonic SNP rs12936511, not previously studied in the context of psychiatric disorders and suicidal behaviors, was significantly transmitted to suicidal males with increased Beck Depression Inventory (BDI) scores (n = 347; P = 0.0028).
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Abnormal behavior
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor T-allele of exonic SNP rs12936511, not previously studied in the context of psychiatric disorders and suicidal behaviors, was significantly transmitted to suicidal males with increased Beck Depression Inventory (BDI) scores (n = 347; P = 0.0028).
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
child abuse behavior
|
|
0.030 |
GeneticVariation |
BEFREE |
We then extended our previously reported interaction with both a CRHR1 SNP (rs110402) and TCA haplotype interacting with child abuse to predict current symptoms (N = 1,059; P = 0.0089).
|
20029939 |
2010 |
|
rs12944712
|
CRHR1;LINC02210-CRHR1
|
Post-Traumatic Stress Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Results indicated that multiple SNPs were associated with acute symptoms at a univariate level, and after correction for multiple testing, rs12944712 was significantly related to acute PTSD symptoms.
|
21508513 |
2011 |
|
rs16940665
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs16940668
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs16940674
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs16940676
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs17425752
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs1876829
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs1876830
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
rs2316765
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |