DRD2, dopamine receptor D2, 1813

N. diseases: 437; N. variants: 42
Disease: Heroin Dependence ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1079597
rs1079597
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0019337
Disease:
Heroin Dependence 		0.020 GeneticVariation BEFREE According to the allele, genotype and haplotype frequency analysis, we observed an association between HD and several DRD2/ANKK1 polymorphisms (rs1800497, rs1800498, rs1079597 and rs4648319); this was most notable in the late-onset HD subgroup. 28854834 2019
dbSNP: rs1079597
rs1079597
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0019337
Disease:
Heroin Dependence 		0.020 GeneticVariation BEFREE In single marker analysis the TaqIA (rs1800497) and TaqIB (rs1079597) variants were associated with heroin dependence. 23840506 2013
dbSNP: rs1076560
rs1076560
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0019337
Disease:
Heroin Dependence 		0.010 GeneticVariation BEFREE Neither rs1076560 nor rs2283265 significantly associated with heroin addiction. 31025317 2019
dbSNP: rs12364283
rs12364283
Entrez Id: 1813;105369501
Gene Symbol: DRD2;LOC105369501
DRD2;LOC105369501
CUI: C0019337
Disease:
Heroin Dependence 		0.010 GeneticVariation BEFREE The enhancer rs12364283</span> occurs more frequently in heroin-dependent cases than controls (MAF 13% vs. 7%, respectively), revealing significant association with heroin addiction (p = 3.0E-06, OR 2.1). 31025317 2019
dbSNP: rs2283265
rs2283265
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0019337
Disease:
Heroin Dependence 		0.010 GeneticVariation BEFREE Neither rs1076560 nor rs2283265 significantly associated with heroin addiction. 31025317 2019
dbSNP: rs4648319
rs4648319
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0019337
Disease:
Heroin Dependence 		0.010 GeneticVariation BEFREE According to the allele, genotype and haplotype frequency analysis, we observed an association between HD and several DRD2/ANKK1 polymorphisms (rs1800497, rs1800498, rs1079597 and rs4648319); this was most notable in the late-onset HD subgroup. 28854834 2019