SERPINB1, serpin family B member 1, 1992

N. diseases: 41; N. variants: 2
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs398312
rs398312
Entrez Id: 1992
Gene Symbol: SERPINB1
SERPINB1
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		G 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs316341
rs316341
Entrez Id: 1992
Gene Symbol: SERPINB1
SERPINB1
CUI: C0002395
Disease:
Alzheimer's Disease 		0.010 GeneticVariation BEFREE Bioinformatics indicate that the intronic SERPINB1 variant (rs316341) affects expression of SERPINB1 in various tissues, including the hippocampus, suggesting that SERPINB1 influences AD through an Aβ-associated mechanism. 28247064 2017