In addition to confirming two associations reported in other ancestry groups, this study identified one new risk-associated locus for glioma on chromosome 12p11.23 (rs10842893, p<sub>meta</sub> = 2.33x10-12, STK38L) as well as a promising association at 15q15-21.1 (rs4774756, p<sub>meta</sub> = 6.12x10-8, RAB27A) in 3,097 glioma cases and 4,362 controls.
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.