DisGeNET - a database of gene-disease associations

GRIK4, glutamate ionotropic receptor kainate type subunit 4, 2900

N. diseases: 41; N. variants: 15

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs12278740

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs1893907

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs1893907

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs2508655

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs4938815

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs56144287

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs56144287

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs74888189

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs74888189

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs79229131

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs79229131

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0016529
Disease:

Forced expiratory volume function

0.700

GeneticVariation

GWASCAT

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

26634245

2015

dbSNP:

rs534517447

Entrez Id:	2900;101929208
Gene Symbol:	GRIK4;LOC101929208

GRIK4;LOC101929208

CUI:	C0036572
Disease:

Seizures

0.700

GeneticVariation

CLINVAR

dbSNP:

rs534517447

Entrez Id:	2900;101929208
Gene Symbol:	GRIK4;LOC101929208

GRIK4;LOC101929208

CUI:	C0856975
Disease:

Autistic behavior

0.700

GeneticVariation

CLINVAR

dbSNP:

rs534517447

Entrez Id:	2900;101929208
Gene Symbol:	GRIK4;LOC101929208

GRIK4;LOC101929208

CUI:	C0454644
Disease:

Delayed speech and language development

0.700

GeneticVariation

CLINVAR

dbSNP:

rs534517447

Entrez Id:	2900;101929208
Gene Symbol:	GRIK4;LOC101929208

GRIK4;LOC101929208

CUI:	C0026351
Disease:

Moderate intellectual disability

0.700

GeneticVariation

CLINVAR

dbSNP:

rs869312699

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0454644
Disease:

Delayed speech and language development

GCT

0.700

GeneticVariation

CLINVAR

dbSNP:

rs869312699

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0036572
Disease:

Seizures

GCT

0.700

GeneticVariation

CLINVAR

dbSNP:

rs869312699

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0856975
Disease:

Autistic behavior

GCT

0.700

GeneticVariation

CLINVAR

dbSNP:

rs869312699

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0026351
Disease:

Moderate intellectual disability

GCT

0.700

GeneticVariation

CLINVAR

dbSNP:

rs11218016

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C1269683
Disease:

Major Depressive Disorder

0.010

GeneticVariation

BEFREE

Strong linkage disequilibrium (LD) was found among rs11218016, rs6589847 and rs56275759, and this block was significantly associated with MDD.

28583584

2017

dbSNP:

rs56275759

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C1269683
Disease:

Major Depressive Disorder

0.010

GeneticVariation

BEFREE

Strong linkage disequilibrium (LD) was found among rs11218016, rs6589847 and rs56275759, and this block was significantly associated with MDD.

28583584

2017

dbSNP:

rs6589847

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C1269683
Disease:

Major Depressive Disorder

0.010

GeneticVariation

BEFREE

Strong linkage disequilibrium (LD) was found among rs11218016, rs6589847 and rs56275759, and this block was significantly associated with MDD.

28583584

2017

dbSNP:

rs4430518

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0036341
Disease:

Schizophrenia

0.010

GeneticVariation

BEFREE

A systematic case-control association study of GRIK4 involving a Scottish population found that three SNPs, rs4935752, rs6589846 and rs4430518, were associated with schizophrenia.

18289755

2008

dbSNP:

rs4935752

Entrez Id:	2900;105369532
Gene Symbol:	GRIK4;LOC105369532

GRIK4;LOC105369532

CUI:	C0036341
Disease:

Schizophrenia

0.010

GeneticVariation

BEFREE

A systematic case-control association study of GRIK4 involving a Scottish population found that three SNPs, rs4935752, rs6589846 and rs4430518, were associated with schizophrenia.

18289755

2008

dbSNP:

rs6589846

Entrez Id:	2900
Gene Symbol:	GRIK4

GRIK4

CUI:	C0036341
Disease:

Schizophrenia

0.010

GeneticVariation

BEFREE

A systematic case-control association study of GRIK4 involving a Scottish population found that three SNPs, rs4935752, rs6589846 and rs4430518, were associated with schizophrenia.

18289755

2008