Source: CURATED ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		G 0.810 GeneticVariation GWASCAT Identification of new susceptibility loci for IgA nephropathy in Han Chinese. 26028593 2015
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		G 0.810 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		G 0.810 GeneticVariation GWASDB We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047). 22197929 2011
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761 2011
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0017661
Disease:
IGA Glomerulonephritis 		G 0.810 GeneticVariation GWASCAT We also found that rs660895 was associated with clinical subtypes of IgAN (P = 0.003), proteinuria (P = 0.025) and IgA levels (P = 0.047). 22197929 2011
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASDB TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. 17804836 2007
dbSNP: rs660895
rs660895
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASCAT TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. 17804836 2007
dbSNP: rs477515
rs477515
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0149678
Disease:
Epstein-Barr Virus Infections 		T 0.800 GeneticVariation GWASCAT A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). 23326239 2013
dbSNP: rs477515
rs477515
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0149678
Disease:
Epstein-Barr Virus Infections 		T 0.800 GeneticVariation GWASDB A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). 23326239 2013
dbSNP: rs9270984
rs9270984
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		T 0.800 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568 2013
dbSNP: rs9270984
rs9270984
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		T 0.800 GeneticVariation GWASCAT Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568 2013
dbSNP: rs9271100
rs9271100
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.800 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568 2013
dbSNP: rs615672
rs615672
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.800 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761 2011
dbSNP: rs9271100
rs9271100
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.800 GeneticVariation GWASCAT Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs9271100
rs9271100
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.800 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
dbSNP: rs477515
rs477515
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. 18758464 2008
dbSNP: rs477515
rs477515
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASDB Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. 18758464 2008
dbSNP: rs615672
rs615672
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.800 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300 2007
dbSNP: rs615672
rs615672
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.800 GeneticVariation GWASDB Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300 2007
dbSNP: rs3021304
rs3021304
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042170
Disease:
Uveomeningoencephalitic Syndrome 		G 0.710 GeneticVariation GWASCAT We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97). 25108386 2014
dbSNP: rs2516049
rs2516049
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0010346
Disease:
Crohn Disease 		0.710 GeneticVariation GWASDB A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. 23266558 2013
dbSNP: rs2858870
rs2858870
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0152268
Disease:
Nodular Sclerosis Classical Hodgkin Lymphoma 		C 0.710 GeneticVariation GWASCAT These SNPs are found on 2 haplotypes associated with NSHL risk (rs204999-rs9268528-rs9268542-rs6903608-rs2858870; AGGCT, OR = 1.7, P = 1.71 × 10(-6); GAATC, OR = 0.4, P = 1.16 × 10(-4)). 22086417 2012
dbSNP: rs2858870
rs2858870
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0152268
Disease:
Nodular Sclerosis Classical Hodgkin Lymphoma 		T 0.710 GeneticVariation GWASCAT These SNPs are found on 2 haplotypes associated with NSHL risk (rs204999-rs9268528-rs9268542-rs6903608-rs2858870; AGGCT, OR = 1.7, P = 1.71 × 10(-6); GAATC, OR = 0.4, P = 1.16 × 10(-4)). 22086417 2012
dbSNP: rs1064713
rs1064713
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0004096
Disease:
Asthma 		A 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019