ICAM1, intercellular adhesion molecule 1, 3383

N. diseases: 737; N. variants: 18
Disease: Ulcerative Colitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5498
rs5498
Entrez Id: 3383;3386
Gene Symbol: ICAM1;ICAM4
ICAM1;ICAM4
CUI: C0009324
Disease:
Ulcerative Colitis 		0.020 GeneticVariation BEFREE This meta-analysis demonstrates that the ICAM-1 K469E polymorphism may be associated with susceptibility to CD in Europeans, but no association was found between ICAM-1 K469E and UC. 25942347 2015
dbSNP: rs5498
rs5498
Entrez Id: 3383;3386
Gene Symbol: ICAM1;ICAM4
ICAM1;ICAM4
CUI: C0009324
Disease:
Ulcerative Colitis 		0.020 GeneticVariation BEFREE The heterozygous genotype K/E469 was observed less frequently (P = 0.001 and 0.037, resp.) than the homozygous genotype E/E469, which was more frequent in Crohn's disease and ulcerative colitis (P = 0.002 and 0.012, respectively). 11726228 2001
dbSNP: rs1799969
rs1799969
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0009324
Disease:
Ulcerative Colitis 		0.010 GeneticVariation BEFREE In contrast, the G241R polymorphism was not found to be associated with susceptibility to either CD or UC. 25942347 2015