CXCL8, C-X-C motif chemokine ligand 8, 3576

N. diseases: 1254; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1126647
rs1126647
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0036690
Disease:
Septicemia
0.010 GeneticVariation BEFREE The male population carrying the homozygote TT genotype and T allele of rs4073, the homozygote CC genotype and C allele of rs2227306 and homozygote AA genotype and A allele of rs1126647 are more susceptible to sepsis, suggesting there is a protective effect in females carrying these genotypes and alleles respectively. 27642120 2016
dbSNP: rs2227306
rs2227306
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0036690
Disease:
Septicemia
0.010 GeneticVariation BEFREE The male population carrying the homozygote TT genotype and T allele of rs4073, the homozygote CC genotype and C allele of rs22</span>27306 and homozygote AA genotype and A allele of rs1126647 are more susceptible to sepsis, suggesting there is a protective effect in females carrying these genotypes and alleles respectively. 27642120 2016
dbSNP: rs4073
rs4073
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0036690
Disease:
Septicemia
0.010 GeneticVariation BEFREE The male population carrying the homozygote TT genotype and T allele of rs4073, the homozygote CC genotype and C allele of rs2227306 and homozygote AA genotype and A allele of rs1126647 are more susceptible to sepsis, suggesting there is a protective effect in females carrying these genotypes and alleles respectively. 27642120 2016