DisGeNET - a database of gene-disease associations

IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs872071

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0023434
Disease:

Chronic Lymphocytic Leukemia

0.840

GeneticVariation

GWASDB

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.

22700719

2012

dbSNP:

rs872071

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0023434
Disease:

Chronic Lymphocytic Leukemia

0.840

GeneticVariation

GWASCAT

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.

22700719

2012

dbSNP:

rs872071

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0855095
Disease:

Small Lymphocytic Lymphoma

0.700

GeneticVariation

GWASCAT

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.

22700719

2012

dbSNP:

rs1050976

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0007570
Disease:

Celiac Disease

0.800

GeneticVariation

GWASCAT

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.

22057235

2011

dbSNP:

rs1050976

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0007570
Disease:

Celiac Disease

0.800

GeneticVariation

GWASDB

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease.

22057235

2011

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C4083212
Disease:

Alopecia, Male Pattern

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C2678038
Disease:

Alopecia, Androgenetic, 2

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C2676272
Disease:

Alopecia, Androgenetic, 3

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0029489
Disease:

Other alopecia

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C4049090
Disease:

Alopecia, Androgenetic, 1

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0162311
Disease:

Androgenetic Alopecia

0.700

GeneticVariation

GWASCAT

Detection and interpretation of shared genetic influences on 42 human traits.

27182965

2016

dbSNP:

rs9391997

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0264408
Disease:

Childhood asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs9391997

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0004096
Disease:

Asthma

0.700

GeneticVariation

GWASCAT

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

30929738

2019

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0002170
Disease:

Alopecia

0.700

GeneticVariation

GWASCAT

Genetic prediction of male pattern baldness.

28196072

2017

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0037290
Disease:

Skin Pigmentation

0.700

GeneticVariation

GWASCAT

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.

25963972

2015

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0018498
Disease:

Hair Color

0.800

GeneticVariation

GWASCAT

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

23548203

2013

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0018498
Disease:

Hair Color

0.800

GeneticVariation

GWASDB

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

23548203

2013

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0406208
Disease:

Suntan

0.700

GeneticVariation

GWASCAT

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

23548203

2013

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0699893
Disease:

Skin carcinoma

0.700

GeneticVariation

GWASDB

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

23548203

2013

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0037290
Disease:

Skin Pigmentation

0.700

GeneticVariation

GWASCAT

Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.

23548203

2013

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0042900
Disease:

Vitiligo

0.700

GeneticVariation

GWASCAT

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.

27723757

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0751676
Disease:

Basal Cell Cancer

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

27539887

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0007117
Disease:

Basal cell carcinoma

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

27539887

2016

dbSNP:

rs12203592

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0206710
Disease:

Basal Cell Neoplasm

0.700

GeneticVariation

GWASCAT

Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

27539887

2016

dbSNP:

rs872071

Entrez Id:	3662
Gene Symbol:	IRF4

IRF4

CUI:	C0023434
Disease:

Chronic Lymphocytic Leukemia

0.840

GeneticVariation

GWASCAT

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.

23770605

2013