IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		G 0.840 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs1050976
rs1050976
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		T 0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0855095
Disease:
Small Lymphocytic Lymphoma 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0553723
Disease:
Squamous cell carcinoma of skin 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma. 27424798 2016
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0406208
Disease:
Suntan 		T 0.700 GeneticVariation GWASCAT Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure. 29739929 2018
dbSNP: rs6906608
rs6906608
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0002171
Disease:
Alopecia Areata 		C 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. 25608926 2015
dbSNP: rs12211228
rs12211228
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color 		0.700 GeneticVariation GWASCAT Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability. 30531825 2018
dbSNP: rs3778607
rs3778607
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color 		A 0.700 GeneticVariation GWASCAT Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability. 30531825 2018
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0162311
Disease:
Androgenetic Alopecia 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C2676272
Disease:
Alopecia, Androgenetic, 3 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C4049090
Disease:
Alopecia, Androgenetic, 1 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C4083212
Disease:
Alopecia, Male Pattern 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0029489
Disease:
Other alopecia 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C2678038
Disease:
Alopecia, Androgenetic, 2 		C 0.700 GeneticVariation GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C1402291
Disease:
Pigmented lesions 		0.010 GeneticVariation BEFREE HERC2/OCA2 rs12913832 and IRF4 rs12203592 influenced both eye colour and the number of iris pigmented lesions. 29315480 2018
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0038868
Disease:
Progressive supranuclear palsy 		0.800 GeneticVariation GWASDB Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0038868
Disease:
Progressive supranuclear palsy 		0.800 GeneticVariation GWASCAT Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
dbSNP: rs1050976
rs1050976
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0026764
Disease:
Multiple Myeloma 		T 0.700 GeneticVariation GWASCAT Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. 30213928 2018
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0007137
Disease:
Squamous cell carcinoma 		T 0.710 GeneticVariation GWASCAT Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma. 26829030 2016
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0025202
Disease:
melanoma 		0.060 GeneticVariation BEFREE In combined analysis of melanoma case-control data from Australia, the UK, and Sweden, the rs12203592(*)C allele was associated with melanoma (odds ratio [OR] 1.15, p = 4 x 10(-3)), most significantly on the trunk (OR = 1.33, p = 2.5 x 10(-5)). 20602913 2010
dbSNP: rs2316515
rs2316515
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0152013
Disease:
Adenocarcinoma of lung (disorder) 		G 0.700 GeneticVariation GWASCAT Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730 2017
dbSNP: rs1050976
rs1050976
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0020676
Disease:
Hypothyroidism 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs2797305
rs2797305
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9391997
rs9391997
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia 		G 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. 26956414 2016