|
rs174547
|
FADS1;FADS2
|
Coronary heart disease
|
|
0.830 |
GeneticVariation |
BEFREE |
rs174547 in FADS1 may contribute to the susceptibility of CHD by altering HDL-C and TG levels in Chinese individuals.
|
22490578 |
2012 |
|
rs174547
|
FADS1;FADS2
|
Coronary heart disease
|
|
0.830 |
GeneticVariation |
BEFREE |
The AA genotype of rs174547 was associated with increased plasma levels of C204n-6, C20:5n-3 and C22:6n-3 and increased δ-5 and δ-6 desaturase activities, but not with CHD risk.
|
22911844 |
2012 |
|
rs174547
|
FADS1;FADS2
|
Coronary heart disease
|
|
0.830 |
GeneticVariation |
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
|
rs174547
|
FADS1;FADS2
|
Coronary heart disease
|
|
0.830 |
GeneticVariation |
BEFREE |
In the secondary analysis, the minor allele of rs174547 in <i>FADS1</i> was associated with significantly lower odds of any ischemic stroke, large-artery stroke, and venous thromboembolism and showed suggestive evidence of inverse association with coronary artery disease, abdominal aortic aneurysm and aortic valve stenosis.
|
31817859 |
2019 |
|
rs174547
|
FADS1;FADS2
|
Coronary heart disease
|
|
0.830 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs968567
|
FADS1;FADS2
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs968567
|
FADS1;FADS2
|
Rheumatoid Arthritis
|
|
0.810 |
GeneticVariation |
BEFREE |
These relate to SNPs associated with Crohn's disease (CD; rs102275) and rheumatoid arthritis (RA; rs968567), which affect the expression of miR-1908-5p (p<sub>rs102275</sub> = 1.44e-20, p<sub>rs968567</sub> = 2.54e-14).
|
30143393 |
2018 |
|
rs174546
|
FADS1;FADS2
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174546
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASDB |
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.
|
19074352 |
2008 |
|
rs174546
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174546
|
FADS1;FADS2
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174546
|
FADS1;FADS2
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174547
|
FADS1;FADS2
|
Lipids measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
|
22286219 |
2012 |
|
rs174547
|
FADS1;FADS2
|
Glucose measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs174547
|
FADS1;FADS2
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs174547
|
FADS1;FADS2
|
Lipids measurement
|
|
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
|
22286219 |
2012 |
|
rs174547
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174547
|
FADS1;FADS2
|
elevated blood glucose level
|
|
0.800 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs174547
|
FADS1;FADS2
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174547
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
rs174548
|
FADS1;FADS2
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174548
|
FADS1;FADS2
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs174548
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs174548
|
FADS1;FADS2
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs174548
|
FADS1;FADS2
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |