LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Disease: Asthma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2844482
rs2844482
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0004096
Disease:
Asthma 		T 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs3093539
rs3093539
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs909253
rs909253
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0004096
Disease:
Asthma 		0.010 GeneticVariation BEFREE A number of studies have shown that the +252A/G polymorphism (rs909253) in the lymphotoxin-α (LT-α) gene is implicated in susceptibility to asthma. 22882567 2012
dbSNP: rs2844484
rs2844484
Entrez Id: 4049;100287329
Gene Symbol: LTA;LOC100287329
LTA;LOC100287329
CUI: C0004096
Disease:
Asthma 		0.010 GeneticVariation BEFREE The association between modeled NO(2) and asthma prevalence was significant for carriers of the most common genotypes of NQO1 rs2917666 [odds ratio (OR) = 1.54; 95% confidence interval (CI), 1.10-2.24], TNFA rs2844484 (OR = 2.02; 95% CI, 1.30-3.27). 20049212 2009