MIR27A, microRNA 27a, 407018

N. diseases: 248; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8101375
rs8101375
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs10422126
rs10422126
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0023508
Disease:
White Blood Cell Count procedure 		A 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs10422126
rs10422126
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0200635
Disease:
Lymphocyte Count measurement 		A 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0678222
Disease:
Breast Carcinoma 		0.100 GeneticVariation BEFREE Our results suggested that rs895819 polymorphism was correlated with increased risk of colorectal cancer and breast cancer, but not all types of cancer. 31838252 2020
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006826
Disease:
Malignant Neoplasms 		0.100 GeneticVariation BEFREE Our results suggested that rs895819 polymorphism was correlated with increased risk of colorectal cancer and breast cancer, but not all types of cancer. 31838252 2020
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.100 GeneticVariation BEFREE Our results suggested that rs895819 polymorphism was correlated with increased risk of colorectal cancer and breast cancer, but not all types of cancer. 31838252 2020
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE Our results suggested that rs895819 polymorphism was correlated with increased risk of colorectal cancer and breast cancer, but not all types of cancer. 31838252 2020
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE Our results suggested that rs895819 polymorphism was correlated with increased risk of colorectal cancer and breast cancer, but not all types of cancer. 31838252 2020
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0678222
Disease:
Breast Carcinoma 		0.100 GeneticVariation BEFREE Conclusion Our data indicate that miR-146a (rs2910164) and miR-27a (rs895819) variants contribute to breast cancer. 29521182 2018
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE The present study indicates that only the rs895819 polymorphism was associated with BC risk. 29782194 2018
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0678222
Disease:
Breast Carcinoma 		0.100 GeneticVariation BEFREE The present study indicates that only the rs895819 polymorphism was associated with BC risk. 29782194 2018
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.100 GeneticVariation BEFREE On the other hand, rs895819 (miR-27a) GG carriers were more susceptible to CRC (OR = 1.47, 95% CI = 1.21-1.78, P = <0.05) in a recessive genetic model. 30447914 2018
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE Conclusion Our data indicate that miR-146a (rs2910164) and miR-27a (rs895819) variants contribute to breast cancer. 29521182 2018
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006826
Disease:
Malignant Neoplasms 		0.100 GeneticVariation BEFREE Furthermore, stratification analyses revealed an association of rs895819</span> with increased cancer risk among Asians (GG <i>vs.</i> AA: OR = 1.17, 95% CI = 1.01-1.36; GG <i>vs.</i> AA/AG: OR = 1.18, 95% CI = 1.03-1.35), but not Caucasians. 29088869 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE Furthermore, stratification analyses revealed an association of rs895819</span> with increased cancer risk among Asians (GG <i>vs.</i> AA: OR = 1.17, 95% CI = 1.01-1.36; GG <i>vs.</i> AA/AG: OR = 1.18, 95% CI = 1.03-1.35), but not Caucasians. 29088869 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.100 GeneticVariation BEFREE To summarize, our results indicated that rs895819 was a protective factor for cancer in Caucasians and could increase colorectal cancer risk but decrease breast cancer risk. 28415619 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0678222
Disease:
Breast Carcinoma 		0.100 GeneticVariation BEFREE C allele in the variant rs895819 is associated with decreased risk of breast cancer. 29128203 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE To summarize, our results indicated that rs895819 was a protective factor for cancer in Caucasians and could increase colorectal cancer risk but decrease breast cancer risk. 28415619 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006826
Disease:
Malignant Neoplasms 		0.100 GeneticVariation BEFREE To summarize, our results indicated that rs895819 was a protective factor for cancer in Caucasians and could increase colorectal cancer risk but decrease breast cancer risk. 28415619 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006826
Disease:
Malignant Neoplasms 		0.100 GeneticVariation BEFREE A meta-analysis was conducted to provide evidence for the effect of microRNA 27a rs895819 on cancer survival. 29100439 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.100 GeneticVariation BEFREE A meta-analysis was conducted to provide evidence for the effect of microRNA 27a rs895819 on cancer survival. 29100439 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.100 GeneticVariation BEFREE However, rs895819 was associated with increased risk of colorectal cancer (GG <i>vs.</i> AA: OR = 1.56, 95% CI = 1.31-1.85; GG <i>vs.</i> AA/AG: OR = 1.53, 95% CI = 1.30-1.79; G <i>vs.</i> A: OR = 1.19, 95% CI = 1.09-1.30) and lung cancer (GG <i>vs.</i> AA/AG: OR = 1.43, 95% CI = 1.00-2.04). 29088869 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE C allele in the variant rs895819 is associated with decreased risk of breast cancer. 29128203 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.100 GeneticVariation BEFREE Interestingly, the [G] allele of rs895819 was significantly associated with decreased risk of breast cancer (G <i>vs.</i> A: OR = 0.91, 95% CI = 0.86-0.97). 29088869 2017
dbSNP: rs895819
rs895819
Entrez Id: 284454;407010;407013;407018
Gene Symbol: LOC284454;MIR23A;MIR24-2;MIR27A
LOC284454;MIR23A;MIR24-2;MIR27A
CUI: C0678222
Disease:
Breast Carcinoma 		0.100 GeneticVariation BEFREE To summarize, our results indicated that rs895819 was a protective factor for cancer in Caucasians and could increase colorectal cancer risk but decrease breast cancer risk. 28415619 2017