MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs243865
rs243865
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0020538
Disease:
Hypertensive disease
0.020 GeneticVariation BEFREE Carriers of rs243865 T allele and rs243866 A allele in MMP-2 were suggested to have increased risks of hypertension. 30684802 2019
dbSNP: rs243865
rs243865
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0020538
Disease:
Hypertensive disease
0.020 GeneticVariation BEFREE The rs243865 T allele was associated with IA presence in univariate (OR 1.18 [95% CI 1.04-1.33], p = .01) and in multi-variable analyses adjusted for smoking and hypertension status (OR 1.16 [95% CI 1.01-1.35], p = .042). 29334797 2018
dbSNP: rs14070
rs14070
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE Increasing urinary cadmium concentrations were positively associated with hypertension risk in a Chinese population, and the associations were modified by polymorphism of rs14070 and rs7201 in gene MMP-2. 30684802 2019
dbSNP: rs243866
rs243866
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE Carriers of rs243865 T allele and rs243866 A allele in MMP-2 were suggested to have increased risks of hypertension. 30684802 2019
dbSNP: rs7201
rs7201
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0020538
Disease:
Hypertensive disease
0.010 GeneticVariation BEFREE Increasing urinary cadmium concentrations were positively associated with hypertension risk in a Chinese population, and the associations were modified by polymorphism of rs14070 and rs7201 in gene MMP-2. 30684802 2019