MYL4, myosin light chain 4, 4635

N. diseases: 26; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs886037778
rs886037778
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C4310636
Disease:
ATRIAL FIBRILLATION, FAMILIAL, 18 		0.700 GeneticVariation UNIPROT A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation. 27066836 2016
dbSNP: rs886037778
rs886037778
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C3468561
Disease:
familial atrial fibrillation 		A 0.700 CausalMutation CLINVAR A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation. 27066836 2016
dbSNP: rs1515751
rs1515751
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0004238
Disease:
Atrial Fibrillation 		0.010 GeneticVariation BEFREE Moreover, the A allele of rs1515751 had a significant association with AF onset. 31406021 2019
dbSNP: rs1515752
rs1515752
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE The prevalence of hypertension was associated with rs1515752, and left atrial size was associated with the genotype of rs2071438. 31406021 2019
dbSNP: rs2071438
rs2071438
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0020538
Disease:
Hypertensive disease 		0.010 GeneticVariation BEFREE The prevalence of hypertension was associated with rs1515752, and left atrial size was associated with the genotype of rs2071438. 31406021 2019
dbSNP: rs4968309
rs4968309
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE C allele and CC genotype of rs4968309 and A allele of rs1515751were associated with AF onset both before and after adjustment of covariation (age, sex, hypertension, and diabetes). 31406021 2019
dbSNP: rs4968309
rs4968309
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE C allele and CC genotype of rs4968309 and A allele of rs1515751were associated with AF onset both before and after adjustment of covariation (age, sex, hypertension, and diabetes). 31406021 2019
dbSNP: rs4968309
rs4968309
Entrez Id: 4635
Gene Symbol: MYL4
MYL4
CUI: C0004238
Disease:
Atrial Fibrillation 		0.010 GeneticVariation BEFREE C allele and CC genotype of rs4968309 inMYL4were associated with AF onset and recurrence. 31406021 2019