NEDD4, NEDD4 E3 ubiquitin protein ligase, 4734

N. diseases: 101; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8032158
rs8032158
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0022548
Disease:
Keloid
0.810 GeneticVariation BEFREE Recently, a genome-wide association study (GWAS) in Japanese population has identified 3 susceptibility loci (rs873549 at 1q41, rs940187 and rs1511412 at 3q22.3, rs8032158 at 15p21.3) for keloid. 23667473 2013
dbSNP: rs8032158
rs8032158
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0022548
Disease:
Keloid
C 0.810 GeneticVariation GWASCAT A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. 20711176 2010
dbSNP: rs8032158
rs8032158
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0022548
Disease:
Keloid
C 0.810 GeneticVariation GWASDB A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population. 20711176 2010
dbSNP: rs1863758
rs1863758
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0005890
Disease:
Body Height
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs1912403
rs1912403
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0040420
Disease:
Tonometry
T 0.700 GeneticVariation GWASCAT Genome-wide association analyses identify new loci influencing intraocular pressure. 29617998 2018
dbSNP: rs1509406
rs1509406
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0013312
Disease:
Dupuytren Contracture
G 0.700 GeneticVariation GWASCAT A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis. 28886342 2017
dbSNP: rs2303579
rs2303579
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0338656
Disease:
Impaired cognition
0.010 GeneticVariation BEFREE Our study showed that in schizophrenia patients of Chinese Han population, the polymorphisms of rs3088077 and rs2303579 loci were related to the pathogenesis of schizophrenia, while the polymorphisms of rs2303579 and rs62043855 loci were associated with cognitive dysfunction. 31849325 2019
dbSNP: rs2303579
rs2303579
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0036341
Disease:
Schizophrenia
0.010 GeneticVariation BEFREE Our study showed that in schizophrenia patients of Chinese Han population, the polymorphisms of rs3088077 and rs2303579 loci were related to the pathogenesis of schizophrenia, while the polymorphisms of rs2303579 and rs62043855 loci were associated with cognitive dysfunction. 31849325 2019
dbSNP: rs3088077
rs3088077
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0338656
Disease:
Impaired cognition
0.010 GeneticVariation BEFREE Our study showed that in schizophrenia patients of Chinese Han population, the polymorphisms of rs3088077 and rs2303579 loci were related to the pathogenesis of schizophrenia, while the polymorphisms of rs2303579 and rs62043855 loci were associated with cognitive dysfunction. 31849325 2019
dbSNP: rs3088077
rs3088077
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0036341
Disease:
Schizophrenia
0.010 GeneticVariation BEFREE Our study showed that in schizophrenia patients of Chinese Han population, the polymorphisms of rs3088077 and rs2303579 loci were related to the pathogenesis of schizophrenia, while the polymorphisms of rs2303579 and rs62043855 loci were associated with cognitive dysfunction. 31849325 2019
dbSNP: rs62043855
rs62043855
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0338656
Disease:
Impaired cognition
0.010 GeneticVariation BEFREE Our study showed that in schizophrenia patients of Chinese Han population, the polymorphisms of rs3088077 and rs2303579 loci were related to the pathogenesis of schizophrenia, while the polymorphisms of rs2303579 and rs62043855 loci were associated with cognitive dysfunction. 31849325 2019
dbSNP: rs2271289
rs2271289
Entrez Id: 4734
Gene Symbol: NEDD4
NEDD4
CUI: C0022548
Disease:
Keloid
0.010 GeneticVariation BEFREE We found three SNPs in two regions showed significant association with keloid in the Chinese Han population: 1q41 (rs873549, P = 3.03×10(-33), OR = 2.05, 95% CI: 1.82-2.31 and rs1442440, P = 9.85×10(-18), OR = 0.56, 95% CI: 0.49-0.64, respectively) and 15q21.3 (rs2271289 located in NEDD4, P = 1.02×10(-11), OR = 0.66, 95% CI: 0.58-0.74). 23667473 2013