|
rs1458766475
|
SELE;C1orf112
|
Arteriopathic disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease.
|
15179350 |
2004 |
|
rs5361
|
SELE;C1orf112
|
Arteriopathic disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease.
|
15179350 |
2004 |
|
rs5361
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation |
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.070 |
GeneticVariation |
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
rs5361
|
SELE;C1orf112
|
Atherosclerosis
|
|
0.070 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs5361
|
SELE;C1orf112
|
Arteriosclerosis
|
|
0.070 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs1458766475
|
SELE;C1orf112
|
Atherosclerosis
|
|
0.060 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs1458766475
|
SELE;C1orf112
|
Arteriosclerosis
|
|
0.060 |
GeneticVariation |
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
rs5355
|
SELE;C1orf112
|
Essential Hypertension
|
|
0.020 |
GeneticVariation |
BEFREE |
A significant association of E-selectin (Leu554Phe) gene and increased expression of E-selectin gene at mRNA and protein levels in patients might be related to the genetic predisposition to develop essential hypertension.
|
29178542 |
2018 |
|
rs1131498
|
SELL;C1orf112
|
Brucellosis
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant difference in F206L polymorphism was found between patients with brucellosis and controls.
|
16585636 |
2006 |
|
rs5361
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation |
BEFREE |
After controlling for other CAD risk factors (plasma total cholesterol, triglyceride, LDL-apolipoprotein B. cigarette smoking and the S128R mutation) by multiple logistic analysis, the G98T mutation in the E-selectin gene was still a significant predictor of premature CAD [p = 0.022, odds ratio (95%, CI)= 3.58 (1.20-10.67)].
|
11168027 |
2001 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.070 |
GeneticVariation |
BEFREE |
After controlling for other CAD risk factors (plasma total cholesterol, triglyceride, LDL-apolipoprotein B. cigarette smoking and the S128R mutation) by multiple logistic analysis, the G98T mutation in the E-selectin gene was still a significant predictor of premature CAD [p = 0.022, odds ratio (95%, CI)= 3.58 (1.20-10.67)].
|
11168027 |
2001 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
rs5361
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
rs1458766475
|
SELE;C1orf112
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
rs5361
|
SELE;C1orf112
|
Myocardial Infarction
|
|
0.040 |
GeneticVariation |
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
rs1458766475
|
SELE;C1orf112
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.
|
23242661 |
2013 |
|
rs5361
|
SELE;C1orf112
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Although there is not association between ICAM1 (G241R and K469E), VCAM1 (T-1591C and T-833C), and E-selectin (S128R) SNPs and susceptibility to GD, higher anti-TPO in E-selectin 128 SR + RR, and lower TSH in ICAM1 469 KE + EE subjects suspect that these genotypes are prone to increased antithyroid autoantibody production with more accentuated TSH suppression in GD.
|
23242661 |
2013 |
|
rs5361
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation |
BEFREE |
Among the Saudi population, The E-selectin p. S128R (g. A561C) polymorphism was associated with angiographic CAD in Univariate analysis, but lost its association in multivariate analysis.
|
16756647 |
2006 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary Artery Disease
|
|
0.070 |
GeneticVariation |
BEFREE |
Among the Saudi population, The E-selectin p. S128R (g. A561C) polymorphism was associated with angiographic CAD in Univariate analysis, but lost its association in multivariate analysis.
|
16756647 |
2006 |
|
rs1458766475
|
SELE;C1orf112
|
Diabetes Mellitus
|
|
0.030 |
GeneticVariation |
BEFREE |
Among women with low levels of subclinical inflammation (C-reactive protein levels below the population median), S128R R allele carriers had a diabetes risk factor-adjusted relative risk of incident diabetes of 1.71 (95% confidence interval, 1.04 to 2.81) relative to those with the SS genotype.
|
15833936 |
2005 |
|
rs5361
|
SELE;C1orf112
|
Diabetes Mellitus
|
|
0.030 |
GeneticVariation |
BEFREE |
Among women with low levels of subclinical inflammation (C-reactive protein levels below the population median), S128R R allele carriers had a diabetes risk factor-adjusted relative risk of incident diabetes of 1.71 (95% confidence interval, 1.04 to 2.81) relative to those with the SS genotype.
|
15833936 |
2005 |
|
rs1458766475
|
SELE;C1orf112
|
Diabetes
|
|
0.020 |
GeneticVariation |
BEFREE |
Among women with low levels of subclinical inflammation (C-reactive protein levels below the population median), S128R R allele carriers had a diabetes risk factor-adjusted relative risk of incident diabetes of 1.71 (95% confidence interval, 1.04 to 2.81) relative to those with the SS genotype.
|
15833936 |
2005 |
|
rs5361
|
SELE;C1orf112
|
Diabetes
|
|
0.020 |
GeneticVariation |
BEFREE |
Among women with low levels of subclinical inflammation (C-reactive protein levels below the population median), S128R R allele carriers had a diabetes risk factor-adjusted relative risk of incident diabetes of 1.71 (95% confidence interval, 1.04 to 2.81) relative to those with the SS genotype.
|
15833936 |
2005 |
|
rs1458766475
|
SELE;C1orf112
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population.
|
15871853 |
2005 |