RET, ret proto-oncogene, 5979

N. diseases: 607; N. variants: 162
Disease: Secondary malignant neoplasm of lymph node ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs74799832
rs74799832
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node 		0.020 GeneticVariation BEFREE An activating M918T RET (c.2753T>C) somatic mutation was identified in a lymph node metastasis. 28068878 2017
dbSNP: rs75873440
rs75873440
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node 		0.020 GeneticVariation BEFREE Genome-wide copy number analysis in a family with p.G533C RET mutation and medullary thyroid carcinoma identified regions potentially associated with a higher predisposition to lymph node metastasis. 24601688 2014
dbSNP: rs74799832
rs74799832
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node 		0.020 GeneticVariation BEFREE In the present work, a comparative genomic hybridization (CGH) study was performed using DNA from a primary tumor in a M918T RET mutation-positive SMTC patient and from its lymph node metastasis to investigate additional genetic alterations. 22676344 2012
dbSNP: rs75873440
rs75873440
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0686619
Disease:
Secondary malignant neoplasm of lymph node 		0.020 GeneticVariation BEFREE Association between a SNP or haplotype and age at diagnosis or presence of lymph node metastasis was tested in 34 G533C-carries with MTC. 19138318 2009